Results 81 to 90 of about 6,774,858 (301)

Singing in the rain: the role of umbrella concepts in library and information science

Information Research: An International Electronic Journal
Introduction. This paper considers the function and use of umbrella concepts within the library and information science (LIS) discipline. Method.
Ian Ruthven, Alison Hicks, Pamela J. McKenzie, Jenny Bronstein, Jette Seiden Hyldegård, Gunilla Widén   +5 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Exploring the Theory of Information Worlds: A Content Analysis of Its Applications and Developments

Journal of Information Science Theory and Practice
This study explores the applications and developments of the theory of information worlds (TIW), developed by Burnett and Jaeger (2008), Jaeger and Burnett (2010), in peer-reviewed research published between 2008 and 2023.
Jonathan M. Hollister, Jisue Lee, Sungjae Park   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Introduction to the special issue on ability beliefs and learning a new language at school

Studies in Second Language Learning and Teaching
This editorial introduces a special issue examining ability beliefs in language learning psychology. The issue presents diverse theoretical perspectives on how learners’ perceptions of their abilities affect language acquisition outcomes.
W. L. Quint Oga-Baldwin, Luke K. Fryer
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Screenplay Business: Managing creativity in script development in the contemporary British independent film industry [PDF]

, 2014
A screenplay is sometimes said to be a blueprint for a film, and its genesis and development is therefore important to our understanding of how films are created.
Bloore, Peter
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Digital Transformation: An Enterprise Transformation Theory Perspective

Australasian Journal of Information Systems
Digital Transformation (DT) has emerged as one of the most talked-about phenomena of the decade. The rush of things around DT also exposes its challenges towards effectively integrating digital technologies into the scheme of things.
Rahul Kumar, Rahul Thakurta
doaj   +1 more source