Results 51 to 60 of about 185,127 (293)

Simulating stochastic fluid dynamics [PDF]

EPJ Web of Conferences
We present simulations of the real time dynamics of a fluid in the vicinity of a critical endpoint in the phase diagram. The relevant hydrodynamic theory is known as model H, and it is expected to describe the long-distance dynamics of QCD matter in the ...
Chattopadhyay Chandrodoy, Ott Josh, Schäfer Thomas, Skokov Vladimir   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Sub-Index for Critical Points of Distance Functions [PDF]

, 2012
Morse theory is based on the idea that a smooth function on a manifold yields data about the topology of the manifold. In this way it provides a tool for visualizing the shape of a space.
Herzog, Barbara
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Internal consistency reliability and construct validity of the Attitude toward Muslim Proximity Index (AMPI): a measure of social distance [PDF]

, 2009
The Attitude toward Muslim Proximity Index (AMPI) is a six-item scale that uses tolerance to different degrees of social distance to assess prejudice towards Muslims. It was tested on 1777 teenage school children from northern England who indicated their
Village, Andrew, Francis, Leslie J., Brockett, Adrian   +2 more
core   +1 more source

FATIGUE LIFE PREDICTION OF NOTCHED STRUCTURE USING COMBINED CRITICAL PLANE-CRITICAL DISTANCE APPROACH (MT)

, 2023
In engineering practice, due to various functional requirements, structures with geometric discontinuities occur widely; in addition, most structures undergo complex multiaxial loads, which drives the development of relevant theories.
GAO JieWei, NIU XiaoPeng, HE JinChao, LIAO Ding, ZHU ShunPeng   +4 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Critical scaling of the quantum Wasserstein distance

Physical Review Research
Distinguishing quantum states with minimal sampling overhead is of fundamental importance to teach quantum data to an algorithm. Recently, the quantum Wasserstein distance emerged from the theory of quantum optimal transport as a promising tool in this ...
Gonzalo Camacho, Benedikt Fauseweh
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

End of the world brane networks for infinite distance limits in CY moduli space

Journal of High Energy Physics
Dynamical Cobordism provides a powerful method to probe infinite distance limits in moduli/field spaces parameterized by scalars constrained by generic potentials, employing configurations of codimension-1 end of the world (ETW) branes.
Roberta Angius
doaj   +1 more source