Results 81 to 90 of about 166,378,206 (284)

Fatigue Life Prediction of Pump Head Materials Based on the Theory of Critical Distances

Shiyou jixie, 2020
To study whether the critical distance theory can reasonably predict the fatigue life of a notched specimen, the finite element model for the chrome-nickel alloy notched specimen of a certain pump head material was established, and the linear elastic ...
Wang Zhaokun, Zhou Sizhu, Zeng Yun, Zhang Si   +3 more
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Destabilizing the Activity System of Online Teaching Through Critical Theory

, 2018
Despite the rapid and prolific uptake of online learning across higher education, the promised positive impact of digital technologies on the quality of learning has mostly failed to materialize.
Wang, VCX, Victor C. X. Wang, Geraldine Torrisi-Steele, Torrisi-Steele, G, Wang, Victor, Torrisi, Rosaria   +5 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The stability of critical distance theory model for high cycle fatigue limit prediction of foreign object damaged blade samples

Scientific Reports
Fan and compressor blades are the critical components of aircraft engine. During flight operations, aircraft engines are inherently susceptible to ingesting debris, resulting in foreign object damage (FOD) that compromises structural integrity of fan and
Yibo Shang, Chen Wang, Xiaosheng Zhang, Bin Li, Lingfeng Wang, Liucheng Zhou, Zhenhua Zhao, Shifeng Wen, Weifeng He   +8 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The Analysis of Stress Raisers Affecting the GFRP Strength at Quasi-Static and Cyclic Loads by the Theory of Critical Distances, Digital Image Correlation, and Acoustic Emission. [PDF]

Polymers (Basel), 2023
Lobanov D, Yankin A, Mullahmetov M, Chebotareva E, Melnikova V.   +4 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

On the application of the Theory of Critical Distances for prediction of fracture in fibre composites [PDF]

Fracture and Structural Integrity, 2010
This paper is concerned with the fracture of composite materials containing stress concentration features such as notches and holes. In particular, it addresses the question of the use of the Theory of Critical Distances (TCD) – a method which is widely ...
David Taylor
doaj  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source