Results 61 to 70 of about 166,378,206 (284)
Fracture and Structural Integrity, 2019 The existence of two singularities related to the stress field at the crack tip and blow-up kinetics of damage localization is considered as the physical basis for the interpretation of the Theory of Critical Distances.
Oleg Naimark
doaj +3 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Critical Theory of Communication
, 2016 This book contributes to the foundations of a critical theory of communication as shaped by the forces of digital capitalism. One of the world's leading theorists of digital media Professor Christian Fuchs explores how the thought of some of the ...
Fuchs, Christian
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Urban theory: new critical perspectives
, 2016 Urban Theory: New Critical Perspectives provides an introduction to innovative critical contributions to the field of urban studies. Chapters offer easily accessible and digestible reviews, and as a reference text Urban Theory is a comprehensive and ...
core +6 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Critical Theory and Libertarian Socialism Realizing the Political Potential of Critical Social Theory [PDF]
, 2016 This volume in the Critical Theory and Contemporary Society series examines the role critical theory plays in today's political, social, and economic crises, showing how it can help to both diagnose and remedy such ...
Masquelier, C
core
Critical Theory and Cultural Studies
, 2018 The aim of this chapter is to present a critical overview of the interrelations, echoes and distinctions that can be identified between critical theory and cultural studies.
Tom Bunyard +2 more
core +1 more source