Results 51 to 60 of about 166,378,206 (284)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

On the application of the Theory of Critical Distances for prediction of fracture in fibre composites

open access: yesFracture and Structural Integrity, 2009
This paper is concerned with the fracture of composite materials containing stress concentration features such as notches and holes. In particular, it addresses the question of the use of the Theory of Critical Distances (TCD) – a method which is widely ...
David Taylor
doaj   +3 more sources

Comparison of local fatigue assessment methods for high-quality butt-welded joints made of high-strength steel

open access: yesForces in Mechanics, 2022
Fatigue strength of welded joints is typically independent of the parent material static strength; however, there are two exceptions from this rule—post-weld treated joints and high-quality joints.
Moritz Braun   +3 more
doaj   +1 more source

Notch Fatigue Life Research Based on Critical Distance Theory

open access: yesApplied Sciences, 2023
Orthotropic anisotropic steel bridge panels are widely used in civil engineering due to their advantages of light deadweight, high ultimate bearing capacity, and wide range of applications. However, their fatigue problem is serious, and the fatigue-resistant design of the steel box girder diaphragm curved cutout is still difficult.
Jifa Chen   +4 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

On the weight of indels in genomic distances [PDF]

open access: yes, 2011
Dias Vieira Braga M, Machado R, Ribeiro LC, Stoye J. On the weight of indels in genomic distances. BMC Bioinformatics. 2011;12(Suppl 9: RECOMB-CG 2011): S13.Background: Classical approaches to compute the genomic distance are usually limited to genomes ...
Machado, Raphael   +3 more
core   +1 more source

Environmentally Assisted Cracking Behavior of S420 and X80 Steels Containing U-notches at Two Different Cathodic Polarization Levels: An Approach from the Theory of Critical Distances

open access: yesMetals, 2019
This paper analyzes, using the theory of critical distances, the environmentally assisted cracking behavior of two steels (S420 and API X80) subjected to two different aggressive environments.
Pablo González   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Exploring Approaches to Data Literacy Through a Critical Race Theory Perspective [PDF]

open access: yes, 2021
In this paper, we describe and analyze a workshop developed for a work training program called DataWorks. In thisworkshop, data workers chose a topic of their interest, sourced and processed data on that topic, and used that data to createpresentations ...
Disalvo, Betsy   +9 more
core   +1 more source

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