Results 121 to 130 of about 4,314,197 (359)

Competencies on sustainability and blue entrepreneurship in university guides: the challenge of a truly blue economy

open access: yesCogent Education
The inclusion of competences related to sustainability and blue entrepreneurship aligns with the 2030 Agenda, a global framework adopted by the United Nations to promote sustainability through 17 Sustainable Development Goals (SDGs).
Miguel-Ángel Fernández-Jiménez   +2 more
doaj   +1 more source

What (actually) matters in literacy education: Contributions from community psychology [PDF]

open access: yes, 2013
This paper describes the critical role community psychology theories played in reframing literacy research involving mainly Māori and Pacific peoples’ extended families and communities.
Furness, Jane Amanda   +4 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Vocational and Liberal Education in Pestalozzi’s Educational Theory

open access: yesPedagogía y Saberes, 2019
Johann Heinrich Pestalozzi’s most popular catchphrase “head, heart, and hand” implies the concept of a holistic combination of all human capabilities as a well-balanced development of intellectual, religious-emotional and physical forces enabled by education.
openaire   +5 more sources

Building professional qualifications as a model of integration and transfer of knowledge [PDF]

open access: yes, 2013
The multi-faceted nature of transformations that occur in modern business encourages the evolution of concepts, methods and tools of competitiveness, as a result of which, dynamic changes are seen in the theory and practice of management.
Kozielski, Robert
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Modeling the mechanisms of readaptation of functional reserves in military personnel with musculoskeletal limb injuries during long-term rehabilitation

open access: yesФізична реабілітація та рекреаційно-оздоровчі технології
Purpose. To evaluate the effectiveness of experimental training models in promoting the readaptation of functional reserves in military personnel with musculoskeletal limb injuries after completing long-term rehabilitation under standard physical therapy
Alina Kizilova   +4 more
doaj   +1 more source

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