Results 51 to 60 of about 152,877 (259)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

El debate entre ciencia y cristianismo en torno al origen del hombre en el pensamiento de Mariano Artigas

Scientia et Fides, 2016
The debate between science and Christianity about the origin of man in the thought of Mariano ArtigasOne of the main intelectual concerns of Professor Artigas was to make clear the relationships between science and faith in bordering fields such as the ...
Carlos Alberto Marmelada
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The nature of culture : an eight-grade model for the evolution and expansion of cultural capacities in hominins and other animals

, 2015
Tracing the evolution of human culture through time is arguably one of the most controversial and complex scholarly endeavors, and a broad evolutionary analysis of how symbolic, linguistic, and cultural capacities emerged and developed in our species is ...
Collard, Mark, Haidle, Miriam Noël, Conard, N., Tennie, Claudio, Bolus, M., Whiten, A., Haidle, M.N., Nowell, April, Haidle, M., Nowell, A., Lombard, Marlize, Haidle, Miriam, Tennie, C., Collard, M., Tennie, C. ; https://orcid.org/, Bolus, Michael, Whiten, Andrew, Garofoli, D., Garafoli, Duilio, Garofoli, Duilio, Conard, N.J., Conard, Nicholas, Lombard, M.   +22 more
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

The quantitative theory of within-host viral evolution

, 2013
During the 1990s, a group of virologists and physicists began development of a quantitative theory to explain the rapid evolution of human immunodeficiency virus type 1 (HIV-1).
Rouzine, Igor M., Weinberger, Leor S.
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Andishe-ye door-o deraz as pioneer of futuristic narration scientific in Iran [PDF]

تاریخ ادبیات, 2016
Andiishe-ye door-o deraz (a high and far sighted mind ) by Mohammad Ali Foruqi (1927) is a narration advocating and contemplative from different aspects. Howevere it dosent suitably presents and studies.
حمیدرضا توکلی
doaj  

A Theory of Galactic Evolution [PDF]

Symposium - International Astronomical Union, 1979
…“there exist many galaxies where most of the light originates in an apparently flat rotating disk, and where the random stellar motions appear to be small compared to the systematic circular motion i.e. they are apparently “cold.” Our own Galaxy is such a system, and it does not seem to suffer any large scale, large amplitude, short-time-scale ...
openaire   +1 more source