Results 171 to 180 of about 46,486 (267)

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

<i>"I Didn't Realise I Knew That!"</i> Higher Education Students' Experiences of Incidental Learning Through OpenWorld Role-Playing Games. [PDF]

Behav Sci (Basel)
Ferriday R.
europepmc   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

The backfiring effect of weak AI safety regulation. [PDF]

Proc Natl Acad Sci U S A
Laufer B, Kleinberg J, Heidari H.
europepmc   +1 more source

Interfacial Electric Field Engineering of High‐Entropy Heterostructures Triggering Self‐Limiting Reconstruction for Industrial‐Scale Electrocatalysis

Advanced Science, EarlyView.
An interfacial electric field engineering strategy is proposed to trigger the self‐limiting surface reconstruction of high‐entropy heterostructures. Driven by this built‐in field, the controlled sacrificial leaching of W evolves a robust active layer, enabling exceptional oxygen evolution performance and ultrastability at ampere‐level current densities
Liang Yan, Yueqi Zhang, Bing Zhang, Jingyi Ye, Hao Li   +4 more
wiley   +1 more source

Integrating Artificial Intelligence with Gamification in Medical Education: A Pedagogically Grounded Framework and Critical Review. [PDF]

Adv Med Educ Pract
Bharatha A, Ojeh N, Campbell MH, Krishnamurthy K, Sangishetti VP, Bhuvanagiri L, Gupta S, Rahman S, Reddy S, Majumder MAA.   +9 more
europepmc   +1 more source

An Interpretable, Data‐Driven, Hierarchical Multi‐Domain Fusion Framework for Classification and Motor Function Scoring in Chronic Ankle Instability

Advanced Science, EarlyView.
An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie, Datao Xu, Zhifeng Zhou, Bas Van Hooren, Huiyu Zhou, Yi Yuan, Xiangli Gao, Monèm Jemni, Liangliang Xiang, Meizi Wang, Justin Fernandez, Tibor J. Goda, Yaodong Gu   +12 more
wiley   +1 more source

A General Upper Bound for the Runtime of a Coevolutionary Algorithm on Impartial Combinatorial Games. [PDF]

Algorithmica
Benford A, Lehre PK.
europepmc   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

ENHANCE (Tailored Intervention for Brain Health and Cognitive Enrichment for Cognitive Health), a Coach-Supported Digital Intervention for Dementia Prevention in Underserved Older Adults: Co-Design and Usability Study. [PDF]

J Med Internet Res
Yu CTK, Livingston G, Allan L, Boczko R, Boex S, Cho Y, Forristal K, Hunter R, Jamison J, Khatun F, Leckstein C, Marston L, Mehta V, Mukadam N, Park HK, Qiu S, Rait G, Rapaport P, Reeve J, Ren L, Schilder AG, Singh A, Sommerlad A, Spillane A, Steed L, Xu M, Yao K, Yu RC, Costafreda SG.   +28 more
europepmc   +1 more source