Results 121 to 130 of about 599,254 (318)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Regarding some Russian and regional exhibition projects of the 2020s in the art space of Kazan: a critical analysis

open access: yesИсторическая этнология
The article analyzes the art space of Kazan as one of Russia’s cultural centers through the lens of contemporary exhibition art projects initiated by museums, exhibition halls, and galleries.
Irina F. Lobasheva   +1 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Argentine Avant-Garde: Experiments With Space in the Works of Pío Collivadino and Florencio Molina Campos

open access: yesИбероамериканские тетради
This paper discusses the concept of avant-garde in arts in two aspects. On the one hand, avant-garde does not always manifest itself as a homogeneous, programmatic and «conscious» movement that defies the long-established processes in the artistic system,
M. G. Fressoli, G. M.M. Schuster
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Philosophy of Psychiatry and Biologism

open access: yesFrontiers in Psychology, 2014
Marco eStier   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Spheres of Influence in International Relations History, Theory and Politics

open access: yes, 2014
Current events happening around the world, especially the 'humanitarian interventions' by NATO and the West within the context of the so-called Arab Spring, make the understanding of the role of spheres of influence in international politics absolutely ...
Hast, Susanna
core  

Exploring the European integration process: Oral History collections on CVCE.eu

open access: yes, 2023
The Luxembourg Centre for Contemporary and Digital History (C2DH), together with the European University Institute (Florence, Italy) and the Max Planck Institute for Legal History and Legal Theory (Frankfurt am Main, Germany), organises this Summer ...
GABELLINI, Marco
core  

Attitudes towards Research Methods in Education: Development of the ATRMQ Scale

open access: yesEducation Sciences
The noticeable lack of knowledge among Spanish university students regarding the disciplinary content of research methodology is notable, despite the considerable potential benefits for curriculum design.
Antonio Matas-Terrón   +3 more
doaj   +1 more source

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