Results 61 to 70 of about 599,254 (318)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Viktor Shklovsky, Bronislaw Malinowski, and the invention of a narrative device: Implications for a history of ethnographic theory

open access: yes, 2020
The advent of Malinowski’s ethnographic theory is inscribed in a wider modernist environment, which set the ground for the emergence of new epistemological projects.
Tateo, Giuseppe
core   +1 more source

What does it take to consent to islet cell xenotransplantation?: Insights from an interview study with type 1 diabetes patients and review of the literature

open access: yesBMC Medical Ethics, 2021
Background The transplantation of porcine islet cells provides a new potential therapy to treat patients with type 1 diabetes mellitus (T1DM). Compared to other biomedical technologies, xenotransplantation stands out in terms of its involvement of ...
Johannes Kögel   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The problem of influences on the monumental art of the Ukrainian-American artist S. Hordynskyi

open access: yesConvergências - Revista de Investigação e Ensino das Artes, 2023
In today’s conditions, namely, the establishment and development of the Ukrainian nation, its cultural and historical origins are of great significance.
Khrystyna Berehovska   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Biological markets, cooperation, and the evolution of morality [PDF]

open access: yes, 2019
Biological market theory has in recent years become an important part of the social evolutionist’s toolkit. This article discusses the explanatory potential and pitfalls of biological market theory in the context of big picture accounts of the evolution ...
Sub History and Philosophy of Science   +3 more
core   +1 more source

The Cultural Heritage of Turkic Peoples in Kazakh Cinema: Intersecting Worlds

open access: yesConservation Science in Cultural Heritage
The aim of the study is to analyze Kazakh and proto-Turkic myths, and mythological aspects in Kazakh cinema, and to assess the influence of other aspects, such as film language and semiotics on film direction and the status of Kazakh cinema in a global ...
Kholganat Murat   +4 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Stones and Other Stuff: A Matter of Concern to Theory of History

open access: yes, 2022
Regazzoni L. Stones and Other Stuff: A Matter of Concern to Theory of History. One more thing.
Regazzoni, Lisa ; https://orcid.org/
core  

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