Results 61 to 70 of about 599,254 (318)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The advent of Malinowski’s ethnographic theory is inscribed in a wider modernist environment, which set the ground for the emergence of new epistemological projects.
Tateo, Giuseppe
core +1 more source
Background The transplantation of porcine islet cells provides a new potential therapy to treat patients with type 1 diabetes mellitus (T1DM). Compared to other biomedical technologies, xenotransplantation stands out in terms of its involvement of ...
Johannes Kögel +4 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The problem of influences on the monumental art of the Ukrainian-American artist S. Hordynskyi
In today’s conditions, namely, the establishment and development of the Ukrainian nation, its cultural and historical origins are of great significance.
Khrystyna Berehovska +4 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Biological markets, cooperation, and the evolution of morality [PDF]
Biological market theory has in recent years become an important part of the social evolutionist’s toolkit. This article discusses the explanatory potential and pitfalls of biological market theory in the context of big picture accounts of the evolution ...
Sub History and Philosophy of Science +3 more
core +1 more source
The Cultural Heritage of Turkic Peoples in Kazakh Cinema: Intersecting Worlds
The aim of the study is to analyze Kazakh and proto-Turkic myths, and mythological aspects in Kazakh cinema, and to assess the influence of other aspects, such as film language and semiotics on film direction and the status of Kazakh cinema in a global ...
Kholganat Murat +4 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Stones and Other Stuff: A Matter of Concern to Theory of History
Regazzoni L. Stones and Other Stuff: A Matter of Concern to Theory of History. One more thing.
Regazzoni, Lisa ; https://orcid.org/
core

