Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
The role and value of ethical frameworks in software development
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Software development is notorious for failure, typically defined as over budget, late delivery and/or poor quality of new information systems (IS) on ...
Dodd, Sean
core
Social capital theory: a cross-cutting analytic for teacher/therapist work in integrating children's services? [PDF]
Reviewing relevant policy, this article argues that the current 'integration interlude' is concerned with reformation of work relations to create new forms of 'social capital'. The conceptual framework of social capital has been used by government policy-
Elspeth McCartney +3 more
core +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Design of 3D stacked wideband Wilkinson power divider based on rectangular micro‐coaxial process
Based on transmission line theory, a 4‐way wideband coupled‐line Wilkinson power divider is designed by the authors, operating from 6 to 18 GHz. It is established by using a novel manufacturing technology with 3D stacked micro‐coaxial line, realising ...
Li‐Jie Xu +6 more
doaj +1 more source
Autonomous fault detection in self-healing systems using Restricted Boltzmann Machines
Funding for this research was provided by the Scottish Informatics and Computer Science Alliance (SICSA).Autonomously detecting and recovering from faults is one approach for reducing the operational complexity and costs associated with managing ...
Barker, Adam David +5 more
core
Classifying Weak, and Strong Components using ROC Analysis with Application to Burn-in [PDF]
Any population of components produced might be composed of two sub-populations: weak components are less reliable, and deteriorate faster whereas strong components are more reliable, and deteriorate slower.
Xie, Min +5 more
core +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Recent Research Progress in Fault Analysis of Complex Electric Power Systems
In this paper, we adopt a novel approach to the fault analysis of complex electric power systems. Electric power system is one of the most complex artificial systems in the world. Its safe, steady, economical and reliable operating plays a very important
WANG, Z., ZHANG, Y., ZHANG, J., MA, J.
doaj +1 more source
Quantum current in dissipative systems
Describing current in open quantum systems can be problematic due to the subtle interplay of quantum coherence and environmental noise. Probing the noise-induced current can be detrimental to the tunneling-induced current and vice versa.
Karen V Hovhannisyan, Alberto Imparato
doaj +1 more source

