Results 41 to 50 of about 12,371 (307)
Numerical Relativity as a New Tool for Fundamental Cosmology
Advances in our understanding of the origin, evolution, and structure of the universe have long been driven by cosmological perturbation theory, model building, and effective field theory.
Anna Ijjas
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THE THEORY OF SCALE RELATIVITY [PDF]
Basing our discussion on the relative character of all scales in nature and on the explicit dependence of physical laws on scale in quantum physics, we apply the principle of relativity to scale transformations. This principle, in combination with its breaking above the Einstein-de Broglie wavelength and time, leads to the demonstration of the ...
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Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Lectures on faster-than-light travel and time travel
These lecture notes were prepared for a 25-hour course for advanced undergraduate students participating in Perimeter Institute's Undergraduate Summer Program.
Barak Shoshany
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This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
A física clássica de cabeça para baixo: como Einstein descobriu a teoria da relatividade especial
Albert Einstein por duas vezes alterou de maneira profunda nossos conceitos de espaço e tempo com a sua teoria da relatividade: primeiro no âmbito da teoria especial de 1905 e depois com a teoria geral de 1915.
Jürgen Renn
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A tale of analogies: a review on gravitomagnetic effects, rotating sources, observers and all that
Gravitoelectromagnetic analogies are somewhat ubiquitous in General Relativity, and they are often used to explain peculiar effects of Einstein’s theory of gravity in terms of familiar results from classical electromagnetism.
Matteo Luca Ruggiero, Davide Astesiano
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Pancreatic theory of relativity...
Pancreatic duct and parenchyma has different benchmarks in nomenclature. The author discusses the proposition to unify the description system of procedures and surgeries within pancreas according to the direction of pancreatic juice natural flow.
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Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source