Results 41 to 50 of about 242,723 (257)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Introduction to Gauge Theory of Gravitation

, 2019
The fundamental interactions of nature, the electroweak and the quantum chromodynamics, are described in the Standard Model by the Gauge Theory under internal symmetries that maintain the invariance of the functional action.
Santos, Wytler Cordeiro dos
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Lectures on faster-than-light travel and time travel

SciPost Physics Lecture Notes, 2019
These lecture notes were prepared for a 25-hour course for advanced undergraduate students participating in Perimeter Institute's Undergraduate Summer Program.
Barak Shoshany
doaj   +1 more source

Scalar-tensor cosmology at the general relativity limit: Jordan vs Einstein frame

, 2008
We consider the correspondence between the Jordan frame and the Einstein frame descriptions of scalar-tensor theory of gravitation. We argue that since the redefinition of the scalar field is not differentiable at the limit of general relativity the ...
C. M. Will, Laur Järv, M. Fierz, Margus Saal, P. Jordan, Piret Kuusk, S. Weinberg, V. Faraoni, V. Faraoni, Y. Fujii   +9 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

A física clássica de cabeça para baixo: como Einstein descobriu a teoria da relatividade especial

Revista Brasileira de Ensino de Física
Albert Einstein por duas vezes alterou de maneira profunda nossos conceitos de espaço e tempo com a sua teoria da relatividade: primeiro no âmbito da teoria especial de 1905 e depois com a teoria geral de 1915.
Jürgen Renn
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Derivation method of numerous dynamics in the Special Theory of Relativity

Open Physics, 2019
The article presents innovative method of deriving dynamics in the Special Theory of Relativity. This method enables to derive infinitely many dynamics in relativistic mechanics. The authors have shown five examples of these derivations.
Szostek Roman
doaj   +1 more source

A tale of analogies: a review on gravitomagnetic effects, rotating sources, observers and all that

Journal of Physics Communications, 2023
Gravitoelectromagnetic analogies are somewhat ubiquitous in General Relativity, and they are often used to explain peculiar effects of Einstein’s theory of gravity in terms of familiar results from classical electromagnetism.
Matteo Luca Ruggiero, Davide Astesiano
doaj   +1 more source