Results 91 to 100 of about 176,595,669 (299)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Concept Design of a Multiwavelength Aerosol Lidar System With Mitigated Diattenuation Effects and Depolarization-Measurement Capability

EPJ Web of Conferences, 2016
It is known that the retrieval of aerosol extinction and backscatter coefficients from lidar data acquired through so-called total-power channels – intended to measure the backscattered power irrespective of the polarization – can be adversely affected ...
Comerón Adolfo, Sicard Michaël, Vidal Eric, Barragán Rubén, Muñoz Constantino, Rodríguez Alejandro, Tiana-Alsina Jordi, Rocadenbosch Francesc, García-Vizcaíno David   +8 more
doaj   +1 more source

Factors affecting online accounting education during the COVID-19 pandemic: an integrated perspective of social capital theory, the theory of reasoned action and the technology acceptance model. [PDF]

Educ Inf Technol (Dordr), 2021
Alshurafat H, Al Shbail MO, Masadeh WM, Dahmash F, Al-Msiedeen JM.   +4 more
europepmc   +1 more source

Theory on Theory [PDF]

, 2020
This chapter assesses three areas of theoretical work: metatheory, via Jason Demers’ The American Politics of French Theory: Derrida, Deleuze, Guattari, and Foucault in Translation and Galin Tihanov’s The Birth and Death of Literary Theory: Regimes of Relevance in Russia and Beyond; three studies that theorize on the history of theory, John E ...
openaire  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

On the Combinatorics of Locally Repairable Codes via Matroid Theory

, 2016
This paper provides a link between matroid theory and locally repairable codes (LRCs) that are either linear or more generally almost affine. Using this link, new results on both LRCs and matroid theory are derived.
Westerbäck, Thomas,, Freij-Hollanti, Ragnar,, Ernvall, Toni,, Westerbäck, Thomas, Freij-Hollanti, Ragnar, Hollanti, Camilla,, Hollanti, Camilla, Ernvall, Toni   +7 more
core   +1 more source

Impact of Diabetes Mellitus on Atrial Fibrillation Recurrence and Major Adverse Cardiac and Cerebrovascular Events following Catheter Ablation

International Journal of Clinical Practice
Introduction. Further evidence is required to understand the impact of preexisting and newly diagnosed diabetes mellitus (DM) on atrial fibrillation (AF) recurrence and major adverse cardiac and cerebrovascular events (MACCEs) following catheter ablation.
Mingjie Lin, Juntao Wang, Bing Rong, Kai Zhang, Tongshuai Chen, Wenqiang Han, Tong Hu, Tianyu Wang, Haonan Deng, Jingquan Zhong, Lin Wu   +10 more
doaj   +1 more source

Correlation-regression models for calculating the weight of small-scale aircraft gas turbine engines

MATEC Web of Conferences, 2018
Several new correlation-regression models of weight calculation for small-scale aircraft gas turbine engines are proposed for their conceptual design stage.
Filinov Evgeny, Kolmakova Daria, Avdeev Sergey, Krasilnikov Sergey   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source