Results 131 to 140 of about 47,521 (285)

Alpha-Emitting Radionuclides: Current Status and Future Perspectives

Pharmaceuticals
The use of radionuclides for targeted endoradiotherapy is a rapidly growing field in oncology. In particular, the focus on the biological effects of different radiation qualities is an important factor in understanding and implementing new therapies ...
Matthias Miederer, Martina Benešová-Schäfer, Constantin Mamat, David Kästner, Marc Pretze, Enrico Michler, Claudia Brogsitter, Jörg Kotzerke, Klaus Kopka, David A. Scheinberg, Michael R. McDevitt   +10 more
doaj   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Diabeto-theranostics.

JPMA. The Journal of the Pakistan Medical Association, 2020
This communication is an interesting and off-beat take on the concept of theranostics, as applied to diabetes care. It proposes the use of the term diabeto-theranostics, to define the combined use of diagnostic and therapeutic modalities, so as to create individualized or personalized treatment strategies in persons with diabetes.
Sanjay, Kalra, Yashdeep, Gupta
openaire   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Nectin4‐targeted molecular imaging in solid tumors: Current status and future perspectives

View
Nectin cell adhesion molecule 4 (Nectin4), a Ca2+‐independent immunoglobulin‐like cell adhesion molecule, plays a role in both physiological and pathological processes.
Yongshun Liu, Wenpeng Huang, Jingwei Zhou, Rachel J. Saladin, Youlan Lei, Weibo Cai, Lei Kang   +6 more
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Neurotensin (8-13) and Neuromedin N Neuropeptides Radiolabelling with Copper-64 Produced on Solid or Liquid Targets

Molecules
On the verge of a theranostic approach to personalised medicine, copper-64 is one of the emerging radioisotopes in nuclear medicine due to its exploitable nuclear and biochemical characteristics.
Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Ivanna Hrynchak, Roxana Tudoroiu-Cornoiu, Sergio J. C. do Carmo, Bogdan Burghelea, Simona Băruță, Ana Rita Almeida, Radu Șerban, Anca Dinischiotu, Antero J. Abrunhosa, Dana Niculae   +12 more
doaj   +1 more source

Theranostic Applications of Au-Ag Nanocages and Nanocomposites [PDF]

, 2012
We report two novel biomedical applications of Au/Ag alloy nanoparticles called nanocages. In the first case, composite nanoparticles consisting of a nanocage core and a mesoporous silica shell doped with a photodynamic sensitizer Yb-2,4 ...
Khlebtsov, B.N., Khlebtsov, N.G.
core  

Therapeutics + diagnostics = theranostics

Tidsskrift for Den norske legeforening, 2023
Torjan, Haslerud, Mona-Elisabeth R, Revheim   +1 more
openaire   +2 more sources

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, EarlyView.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source