Results 21 to 30 of about 38,320 (161)

Fundamentals and Applications of Focused Ultrasound-Assisted Cancer Immune Checkpoint Inhibition for Solid Tumors

Pharmaceutics
Despite spectacular clinical successes across several cancer types, immune checkpoint inhibition is effective only in subgroups of patients and suffers from significant systemic toxicities, highlighting the need to understand and locally overcome the ...
Sepideh Jahangiri, François Yu
doaj   +1 more source

Bimodality imaging as a companion to evaluate antitumour efficacy of TH-302 in experimental chondrosarcoma

EJNMMI Research
Background The hypoxic status of cancer tumour is disparate within tumour microenvironment and is considered as the main cause of treatment resistance. Chondrosarcoma, a type of bone cancer, combines heterogonous tumour microenvironment and resistance to
Roxane Autissier, Guilhem Pagés, Erwan Boutault, Jean-Marie Bonny, Sébastien Schmitt, Philippe Auzeloux, Yannick Bidet, Flora Ponelle-Chachuat, Aurélie Dutour, Elisabeth Miot-Noirault, Leslie Mazuel   +10 more
doaj   +1 more source

Theranostic Agents

, 2022
A theranostic agent can be used in both photoacoustic imaging (PAI) and photothermal therapy (PTT) applications The theranostic agent can include a small molecule, organic compound with absorption in the near-infrared (NIR) inter­rogation window (700-900
Ding, Dan, Tang, Benzhong, Qi, Ji
core  

Nanoparticles as a Tool in Neuro-Oncology Theranostics

Pharmaceutics, 2021
The rapid growth of nanotechnology and the development of novel nanomaterials with unique physicochemical characteristics provides potential for the utility of nanomaterials in theranostics, including neuroimaging, for identifying neurodegenerative ...
Andrea L. Klein, Grant Nugent, John Cavendish, Werner J. Geldenhuys, Krishnan Sriram, Dale Porter, Ross Fladeland, Paul R. Lockman, Jonathan H. Sherman   +8 more
doaj   +1 more source

Step-by-Step Design of New Theranostic Nanoformulations: Multifunctional Nanovectors for Radio-Chemo-Hyperthermic Therapy under Physical Targeting

Molecules, 2021
While investigating the possible synergistic effect of the conventional anticancer therapies, which, taken individually, are often ineffective against critical tumors, such as central nervous system (CNS) ones, the design of a theranostic nanovector able
Shoeb Anwar Ansari, Eleonora Ficiarà, Federico D’Agata, Roberta Cavalli, Lucia Nasi, Francesca Casoli, Franca Albertini, Caterina Guiot   +7 more
doaj   +1 more source

Carbon nanomaterials as versatile platforms for theranostic applications

, 2017
Theranostic nanomedicine, utilizing state-of-the-art, multifaceted nanomaterials and devices with therapeutic and diagnostic dual functions, has emerged as a highly attractive and promising new field of medicine.
Chaenyung Cha, Jang, Jinhyeong, Mirae Kim, Kim, Mirae, Cha, Chaenyung, Jinhyeong Jang   +5 more
core   +1 more source

Functionalization of a Triazine Dendrimer Presenting Four Maleimides on the Periphery and a DOTA Group at the Core

Molecules, 2016
A readily and rapidly accessible triazine dendrimer was manipulated in four steps with 23% overall yield to give a construct displaying four maleimide groups and DOTA.
Changsuk Lee, Kun Ji, Eric E. Simanek
doaj   +1 more source

Mesoporous Silica Nanoparticles: Types, Synthesis, Role in the Treatment of Alzheimer’s Disease, and Other Applications

Pharmaceutics, 2023
Globally, many individuals struggle with Alzheimer’s disease (AD), an unrelenting and incapacitating neurodegenerative condition. Despite notable research endeavors, effective remedies for AD remain constrained, prompting the exploration of innovative ...
Bhagavathi Sundaram Sivamaruthi, Devesh U. Kapoor, Rajiv R. Kukkar, Mansi Gaur, Gehan M. Elossaily, Bhupendra G. Prajapati, Chaiyavat Chaiyasut   +6 more
doaj   +1 more source

Synthesis of Self-Immolative Rhodamine Based Theranostic Agent [PDF]

, 2020
Theranostic agents, a class of molecules that simultaneously serve both a diagnostic and therapeutic function, enable in vivo imaging for early diagnosis and targeted drug delivery within a single entity.
Garrison, Nathaniel, Alexander, Jonathan, Rivera, Alessandra   +2 more
core  

Spray-deployable microenvironment-adaptive nanozyme interface for anti-biofilm and redox-regulated chronic wound healing

Materials & Design
Chronic wounds are characterized by persistent bacterial infection, oxidative stress, and impaired tissue regeneration, which require dynamic therapeutic interventions throughout the healing process.
Junjian Zhao, Han Xie, Yangcui Qu, Yitong Zhou, Shiyu Tan, Guannan Wang   +5 more
doaj   +1 more source