Results 51 to 60 of about 47,521 (285)

Lignin-Mediated Dual Conductive Hydrogels with High Conductivity, Antibacterial Activity and Biocompatibility for Chronic Wound Repair

Gels
In recent years, conductive polymer hydrogels based on polypyrrole (PPy) combined with electrical stimulation (ES) have emerged as a promising approach for chronic wound repair.
Jianhong Lin, Mengyao Chen, Wei Zhao, Shengyu Zhang, Jialin Liu, Yang Zhou, Lei Jiang, Jiantao Zhang   +7 more
doaj   +1 more source

Sphingolipidomics in Translational Sepsis Research–Biomedical Considerations and Perspectives

Frontiers in Medicine, 2021
Scientific Background: Sphingolipids are a highly diverse group of lipids with respect to physicochemical properties controlling either structure, distribution, or function, all of them regulating cellular response in health and disease.
Ralf A. Claus, Markus H. Graeler, Markus H. Graeler, Markus H. Graeler   +3 more
doaj   +1 more source

Preclincial evaluation of Gold-DTDTPA Nanoparticles As Theranostic Agents In Prostate Cancer Radiotherapy [PDF]

, 2016
International audienceAim: Gold nanoparticles have attracted significant interest in cancer diagnosis and treatment. Herein, we evaluated the theranostic potential of dithiolated diethylenetriamine pentaacetic acid (DTDTPA) conjugated AuNPs (Au@DTDTPA ...
Bazzi, Rana, Butterworth, Karl T, Chaudhary, Pankaj, Coulter, Jonathan A, Ghita, Mihaela, Jimenez-Sanchez, Gloria, McCarthy, Helen O, McGarry, Conor K, Nicol, James R, Prise, Kevin M, Rosa, Soraia, Roux, Stéphane, Tillement, Olivier   +12 more
core   +4 more sources

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

Hemocompatibility and Biomedical Potential of Poly(Gallic Acid) Coated Iron Oxide Nanoparticles for Theranostic Use [PDF]

, 2015
Polyacid covered core-shell iron oxide nanoparticles were designed for potential use in biomedicine with special attention to theranostics - magnetic resonance imaging (MRI), magnetic hyperthermia and magnetic drug targeting. The magnetite nanoparticles
Alexiou, Christoph, Farkas, Katalin, Földesi, Imre, Illés, Erzsébet, Janko, Christina, Nesztor, Dániel, Szekeres, Márta, Tombácz, Etelka, Tóth, Ildikó Y., Zupkó, István   +9 more
core   +1 more source

Hybrid Microdiscs for Magnetically Induced Non‐Cytotoxic Thermal Actuation and Programmable Biomolecule Delivery

Advanced Functional Materials, EarlyView.
Hybrid magnetic microdiscs with customizable size and composition are engineered through refined photolithography and LbL assembly. Embedded Fe3O4 nanoparticles enable localized, non‐cytotoxic heating, while protein cargos can be incorporated in tunable quantities.
Daniela Iglesias‐Rojas, Danny Villanueva, Jon Mentxaka‐Salgado, Nerea Lete, Ane Olazagoitia‐Garmendia, Eduardo Fernández, Iñaki Orue, Alfredo García‐Arribas, Maria Luisa Fdez‐Gubieda, Ainara Castellanos‐Rubio, Robert Morel, Bernard Dieny, Maite Insausti, Idoia Castellanos‐Rubio   +13 more
wiley   +1 more source

Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics [PDF]

, 2019
Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR ...
Beattie, Bradley J., Beattie, Kai A., Elgqvist, Jörgen, Eriksson, Sophie E., Larsson, Erik, Strand, Sven-Erik, Thorek, Daniel L. J., Timmermand, Oskar Vilhelmsson, Tran, Thuy A., Ulmert, David, Örbom, Anders   +10 more
core   +2 more sources

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Modulation of αv integrins by lebecetin, a viper venom-derived molecule, in experimental neuroinflammation and demyelination models

Scientific Reports
Several neurodegenerative diseases, such as multiple sclerosis and Parkinson’s disease, are linked to alterations in myelin content or structure. Transmembrane receptors such as integrins could be involved in these alterations.
Nour-elhouda Neili, Zaineb AbdelKafi-Koubaa, Jed Jebali, Khouloud Kaidi, Ghada Sahraoui, Melika Ben Ahmed, Najet Srairi-Abid, Naziha Marrakchi, Raoudha Doghri, Ines ELBini   +9 more
doaj   +1 more source

Nanoparticles as a Tool in Neuro-Oncology Theranostics

Pharmaceutics, 2021
The rapid growth of nanotechnology and the development of novel nanomaterials with unique physicochemical characteristics provides potential for the utility of nanomaterials in theranostics, including neuroimaging, for identifying neurodegenerative ...
Andrea L. Klein, Grant Nugent, John Cavendish, Werner J. Geldenhuys, Krishnan Sriram, Dale Porter, Ross Fladeland, Paul R. Lockman, Jonathan H. Sherman   +8 more
doaj   +1 more source