Results 51 to 60 of about 38,320 (161)

Cellular Uptake and Photo-Cytotoxicity of a Gadolinium(III)-DOTA-Naphthalimide Complex “Clicked” to a Lipidated Tat Peptide

open access: yesMolecules, 2016
A new bifunctional macrocyclic chelator featuring a conjugatable alkynyl-naphthalimide fluorophore pendant group has been prepared and its Gd(III) complex coupled to a cell-penetrating lipidated azido-Tat peptide derivative using Cu(I)-catalysed “click ...
William I. O’Malley   +7 more
doaj   +1 more source

Exosomes and Extracellular Vesicles as Emerging Theranostic Platforms in Cancer Research

open access: yesCells, 2020
Exosomes are endosome-derived nanovesicles produced by healthy as well as diseased cells. Their proteic, lipidic and nucleic acid composition is related to the cell of origin, and by vehiculating bioactive molecules they are involved in cell-to-cell ...
Giorgia Ailuno   +4 more
doaj   +1 more source

Copper-64: a real theranostic agent

open access: yes, 2018
Bianca Gutfilen,1 Sergio AL Souza,1 Gianluca Valentini2 1Department of Radiology, School of Medicine, Laboratório de Marcação de Células e Moléculas (LMCM), Universidade Federal do Rio de Janeiro, Rio de Janeiro ...
Gutfilen B, Valentini G, Souza SAL
core  

Brain-on-a-chip: an emerging platform for studying the nanotechnology-biology interface for neurodegenerative disorders

open access: yesJournal of Nanobiotechnology
Neurological disorders have for a long time been a global challenge dismissed by drug companies, especially due to the low efficiency of most therapeutic compounds to cross the brain capillary wall, that forms the blood-brain barrier (BBB) and reach the ...
Raquel O. Rodrigues   +2 more
doaj   +1 more source

8-Anilino-1-naphthalenesulfonate-Conjugated Carbon-Coated Ferrite Nanodots for Fluoromagnetic Imaging, Smart Drug Delivery, and Biomolecular Sensing

open access: yesPharmaceutics
Background: Superparamagnetic properties and excitation independence have been incorporated into carbon-decorated manganese ferrite nanodots (MnFe@C) to introduce an economical and safer multimodal agent for use in both T1-T2 MRI and fluorescence-based ...
Anbazhagan Thirumalai   +5 more
doaj   +1 more source

Recent Advances in Nanotechnology-Based Approaches for Ferroptosis Therapy and Imaging Diagnosis in Pancreatic Cancer

open access: yesPharmaceutics
Pancreatic cancer is a highly lethal malignant tumor characterized by challenges in early diagnosis and limited therapeutic options, leading to an exceptionally low clinical cure rate.
Xiaoyan Yang   +4 more
doaj   +1 more source

Dual-Functionalized Theranostic Nanocarriers

open access: yes, 2016
Nanocarriers with the ability to spatially organize chemically distinct multiple bioactive moieties will have wide combinatory therapeutic and diagnostic (theranostic) applications.
Karla Santacruz Gomez (2812828)   +15 more
core   +1 more source

Theranostic nanoparticles based on bioreducible polyethylenimine-coated iron oxide for reduction-responsive gene delivery and magnetic resonance imaging

open access: yes, 2014
Dan Li,1,* Xin Tang,2,* Benjamin Pulli,1 Chao Lin,2 Peng Zhao,2 Jian Cheng,2 Zhongwei Lv,1 Xueyu Yuan,1 Qiong Luo,1 Haidong Cai,1 Meng Ye1 1Department of Nuclear Medicine, Shanghai 10th People’s Hospital, 2Shanghai East Hospital, The Institute for
Lv Z   +10 more
core  

Multi-dye theranostic nanoparticle platform for bioimaging and cancer therapy [PDF]

open access: yes, 2012
Amit K Singh,1,2 Megan A Hahn,2 Luke G Gutwein,3 Michael C Rule,4 Jacquelyn A Knapik,5 Brij M Moudgil,1,2 Stephen R Grobmyer,3 Scott C Brown,2,61Department of Materials Science and Engineering, College of Engineering, 2Particle Engineering Research ...
Singh AK   +7 more
core  

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