Results 111 to 120 of about 37,410 (291)

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

open access: yesAngewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini   +13 more
wiley   +2 more sources

Multiwalled Carbon Nanotubes Interact with Macrophages and Influence Tumor Progression and Metastasis

open access: yesTheranostics, 2012
Macrophages are one of the most important types of immune effector cells and are closely associated with tumor progression and metastasis. In this work, we investigated the influences of oxidized multiwalled carbon nanotubes (o-MWCNT) on macrophages that
Man Yang, Jie Meng, Xuelian Cheng, Jing Lei, Hua Guo, Weiqi Zhang, Hua Kong, Haiyan Xu
doaj  

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

open access: yesAdvanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu   +7 more
wiley   +1 more source

Theranostic Potential of an NAD(P)H‐Activatable Fluorophore: Assessing Cancer Aggressiveness and Triggering Apoptosis

open access: yesAngewandte Chemie, EarlyView.
DE‐CQ, an NAD(P)H‐activatable theranostic probe, enables the quantification of cancer aggressiveness via glucose‐stimulated fluorescence imaging and selectively induces apoptosis. Its multifaceted efficacy is demonstrated across 2D cells, 3D spheroids, and in vivo models.
Yujin Cha   +11 more
wiley   +2 more sources

Sodium Iodide Symporter for Nuclear Molecular Imaging and Gene Therapy: From Bedside to Bench and Back

open access: yesTheranostics, 2012
Molecular imaging, defined as the visual representation, characterization and quantification of biological processes at the cellular and subcellular levels within intact living organisms, can be obtained by various imaging technologies, including nuclear
Byeong-Cheol Ahn
doaj  

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen   +8 more
wiley   +1 more source

Industry strategies on theranostics: Need for structural alignment [PDF]

open access: yes, 2007
Theranostics is said to change the way patients will manage their disease. Such a change assumes that diagnostics and therapeutics become increasingly linked based on genetic information.
Boon, Wouter P C   +3 more
core   +1 more source

In Vivo Monitoring of Liver Damage Using Caspase-3 Probe

open access: yesTheranostics, 2012
Real-time monitoring of cellular and organ conditions improves our understanding of various physiopathological phenomena. Such monitoring is expected to provide important alternatives for clinical diagnosis and therapy.
Michitaka Ozaki, Sanae Haga, Takeaki Ozawa
doaj  

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

open access: yesAdvanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Theranostic Potential of Oncolytic Vaccinia Virus

open access: yesTheranostics, 2012
Biological cancer therapies, such as oncolytic, or replication-selective viruses have advantages over traditional therapeutics as they can employ multiple different mechanisms to target and destroy cancers (including direct cell lysis, immune activation ...
Juan J Rojas, Steve H Thorne
doaj  

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