Results 121 to 130 of about 40,969 (293)

Vascular Endothelial Growth Factor-Delivery Systems for Cardiac Repair: An Overview

open access: yesTheranostics, 2012
Since the discovery of the Vascular Endothelial Growth Factor (VEGF) and its leading role in the angiogenic process, this has been seen as a promising molecule for promoting neovascularization in the infarcted heart. However, even though several clinical
Teresa Simón-Yarza, Fabio R. Formiga, Esther Tamayo, Beatriz Pelacho, Felipe Prosper, María J. Blanco-Prieto
doaj  

Click‐to‐Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds

open access: yesAngewandte Chemie International Edition, EarlyView.
Click chemistry has evolved from making covalent connections to also breaking bonds. Here, a cascade assembly is reported that combines these maneuvers to build multifunctional biomolecular scaffolds in a modular one‐pot reaction. The unifying azide release‐tetrazine hub clicks with a trans‐cyclooctene tag, rapidly liberates N,N‐dimethylaniline to ...
Markus Staudt   +9 more
wiley   +1 more source

Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics

open access: yes, 2018
Smart gold nanoparticle-stabilized ultrasound microbubbles (SAuMBs) having diagnostic (US and PAT) and therapeutic (PTT) effects were applied as cancer theranostics.
Guofeng Zhang   +6 more
core   +1 more source

Exploring Theranostic Potentials of Radioiodinated Hypericin in Rodent Necrosis Models

open access: yesTheranostics, 2012
Objectives: The present animal experiments were conducted to evaluate radioiodinated Hypericin (Hyp) for its regional distribution as well as theranostic potentials.Materials and Methods: Rat models of reperfused liver infarction (RLI) and hepatic ...
Junjie Li, Marlein Miranda Cona, Feng Chen, Yuanbo Feng, Lin Zhou, Jie Yu, Johan Nuyts, Peter de Witte, Jian Zhang, Uwe Himmelreich, Alfons Verbruggen, Yicheng Ni
doaj  

A 68Ga‐Substituted Keggin Phosphotungstate as an Intrinsically Radiolabeled Inorganic PET Tracer for Cell Tracking

open access: yesAngewandte Chemie International Edition, EarlyView.
A 68Ga‐substituted Keggin polyoxometalate (Cs68GaPW11) acts as a fully inorganic, self‐tracing PET tracer. 68Ga is locked within the cluster's outer coordination sphere for radiochemical stability, while its membrane‐interacting surface promotes spontaneous membrane association and progressive intracellular accumulation in mammalian cells ...
Ella Duvanova   +5 more
wiley   +1 more source

Crystalline assembly of gold nanoclusters for mitochondria targeted cancer theranostics

open access: yes, 2018
Herein, we report the formation of a crystalline assembly of gold (Au) nanoclusters for cancer theranostics via active targeting of mitochondria.
Srestha Basu   +7 more
core   +1 more source

Innate Immunity Derived Factors as External Modulators of the CXCL12 - CXCR4 Axis and Their Role in Stem Cell Homing and Mobilization

open access: yesTheranostics, 2013
The α-chemokine CXCL12 (stromal derived factor-1; SDF-1) and its corresponding GαI protein-coupled CXCR4 receptor axis play an important role in retention of hematopoietic stem progenitor cells (HSPCs) in bone marrow (BM) stem cell niches ...
Mariusz Z. Ratajczak, Karol Serwin, Gabriela Schneider
doaj  

Editorial: Theranostic nanomaterials

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Wansong Chen   +6 more
openaire   +3 more sources

Spatial Proteomics Identifies Distinct Synovial Microenvironments in Hip and Knee Osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis (OA) is a heterogeneous joint disease, yet mechanistic insights derive predominantly from knee OA and are often extrapolated to other joints. We investigated joint‐associated differences in the spatial molecular organization of hip and knee OA synovium.
Peng Xie   +9 more
wiley   +1 more source

Low Molecular Weight Hydroxyethyl Chitosan-Prednisolone Conjugate for Renal Targeting Therapy: Synthesis, Characterization and In Vivo Studies

open access: yesTheranostics, 2012
To further evaluate the potential renal targeting profile of low molecular weight hydroxyethyl chitosan (LMWHC) we developed before, prednisolone (Pre) was conjugated with LMWHC by EDC/NHS chemistry to improve the therapeutic effect of glucocorticoids in
Xia-kai He, Zhi-xiang Yuan, Xiao-juan Wu, Chao-qun Xu, Wan-yu Li
doaj  

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