Results 31 to 40 of about 40,969 (293)

Theranostic DNAzymes

open access: yesTheranostics, 2017
DNAzymes are catalytically active DNA molecules that are obtained via in vitro selection. RNA-cleaving DNAzymes have attracted significant attention for both therapeutic and diagnostic applications due to their excellent programmability, stability, and activity. They can be designed to cleave a specific mRNA to down-regulate gene expression.
Zhou, Wenhu, Ding, Jinsong, Liu, Juewen
openaire   +2 more sources

The Theranostic Genome [PDF]

open access: yesNature Communications
Theranostic drugs represent an emerging path to deliver on the promise of precision medicine. However, bottlenecks remain in characterizing theranostic targets, identifying theranostic lead compounds, and tailoring theranostic drugs. To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be ...
Xiaoying Xu   +9 more
openaire   +3 more sources

Design of Magnetic Nanoplatforms for Cancer Theranostics

open access: yes, 2022
Cancer is the top cause of death globally. Developing smart nanomedicines that are capable of diagnosis and therapy (theranostics) in one–nanoparticle systems are highly desirable for improving cancer treatment outcomes.
Tingbin Zhang   +5 more
core   +2 more sources

3D Cell Printed Tissue Analogues: A New Platform for Theranostics [PDF]

open access: yes, 2017
Stem cell theranostics has received much attention for noninvasively monitoring and tracing transplanted therapeutic stem cells through imaging agents and imaging modalities. Despite the excellent regenerative capability of stem cells, their efficacy has
YEONG, JIN CHOI   +7 more
core   +1 more source

Targeting neuropilin-1 interactions is a promising anti-tumor strategy

open access: yesChinese Medical Journal, 2021
. Neuropilins (NRP1 and NRP2) are multifunctional receptor proteins that are involved in nerve, blood vessel, and tumor development. NRP1 was first found to be expressed in neurons, but subsequent studies have demonstrated its surface expression in cells
Shao-Dan Liu   +4 more
doaj   +1 more source

Recognition of G-quadruplex topology through hybrid binding with implications in cancer theranostics

open access: yes, 2020
The selective recognition and imaging of oncogene specific G-quadruplex (GQ) structures holds great promise in the development of diagnostic therapy (theranostics) for cancer and has been challenging due to their structural dynamics and diversity.
Suseela, Yelisetty Venkata,   +3 more
core   +1 more source

Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics

open access: yes, 2020
In the light of theranostics/radiotheranostics and prospective of personalized medicine in diabetes and oncology, this review presents prior and current advances in the development of radiolabeled imaging and radiotherapeutic exendin-based agents ...
Velikyan, Irina   +5 more
core   +1 more source

PLGA-based drug delivery system for combined therapy of cancer: research progress

open access: yesMaterials Research Express, 2021
In recent years, PLGA micro/nano particle drug delivery systems has been widely used in cancer treatment. According to the unique properties of PLGA, carriers of various structures are designed to keep the function of drugs or bioactive substances ...
Zhang Ruirui   +6 more
doaj   +1 more source

A Dual Targeting Magnetic Nanoparticle for Human Cancer Detection

open access: yesNanoscale Research Letters, 2019
Malignant tumors are a major threat to human life and high lymphatic vessel density is often associated with metastatic tumors. With the discovery of molecules targeted at the lymphatic system such as lymphatic vessel endothelial hyaluronan receptor 1 ...
Siwen Wu   +9 more
doaj   +1 more source

Nanoparticle-Based Theranostics: Simultaneous Diagnosis and Treatment

open access: yes, 2023
Nanoparticle-based theranostics have emerged as a revolutionary approach in the field of medicine, offering the potential for simultaneous diagnosis and treatment of various diseases.
Pasderhsh Servushan
core   +1 more source

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