Results 31 to 40 of about 40,969 (293)
DNAzymes are catalytically active DNA molecules that are obtained via in vitro selection. RNA-cleaving DNAzymes have attracted significant attention for both therapeutic and diagnostic applications due to their excellent programmability, stability, and activity. They can be designed to cleave a specific mRNA to down-regulate gene expression.
Zhou, Wenhu, Ding, Jinsong, Liu, Juewen
openaire +2 more sources
Theranostic drugs represent an emerging path to deliver on the promise of precision medicine. However, bottlenecks remain in characterizing theranostic targets, identifying theranostic lead compounds, and tailoring theranostic drugs. To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be ...
Xiaoying Xu +9 more
openaire +3 more sources
Design of Magnetic Nanoplatforms for Cancer Theranostics
Cancer is the top cause of death globally. Developing smart nanomedicines that are capable of diagnosis and therapy (theranostics) in one–nanoparticle systems are highly desirable for improving cancer treatment outcomes.
Tingbin Zhang +5 more
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3D Cell Printed Tissue Analogues: A New Platform for Theranostics [PDF]
Stem cell theranostics has received much attention for noninvasively monitoring and tracing transplanted therapeutic stem cells through imaging agents and imaging modalities. Despite the excellent regenerative capability of stem cells, their efficacy has
YEONG, JIN CHOI +7 more
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Targeting neuropilin-1 interactions is a promising anti-tumor strategy
. Neuropilins (NRP1 and NRP2) are multifunctional receptor proteins that are involved in nerve, blood vessel, and tumor development. NRP1 was first found to be expressed in neurons, but subsequent studies have demonstrated its surface expression in cells
Shao-Dan Liu +4 more
doaj +1 more source
Recognition of G-quadruplex topology through hybrid binding with implications in cancer theranostics
The selective recognition and imaging of oncogene specific G-quadruplex (GQ) structures holds great promise in the development of diagnostic therapy (theranostics) for cancer and has been challenging due to their structural dynamics and diversity.
Suseela, Yelisetty Venkata, +3 more
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Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics
In the light of theranostics/radiotheranostics and prospective of personalized medicine in diabetes and oncology, this review presents prior and current advances in the development of radiolabeled imaging and radiotherapeutic exendin-based agents ...
Velikyan, Irina +5 more
core +1 more source
PLGA-based drug delivery system for combined therapy of cancer: research progress
In recent years, PLGA micro/nano particle drug delivery systems has been widely used in cancer treatment. According to the unique properties of PLGA, carriers of various structures are designed to keep the function of drugs or bioactive substances ...
Zhang Ruirui +6 more
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A Dual Targeting Magnetic Nanoparticle for Human Cancer Detection
Malignant tumors are a major threat to human life and high lymphatic vessel density is often associated with metastatic tumors. With the discovery of molecules targeted at the lymphatic system such as lymphatic vessel endothelial hyaluronan receptor 1 ...
Siwen Wu +9 more
doaj +1 more source
Nanoparticle-Based Theranostics: Simultaneous Diagnosis and Treatment
Nanoparticle-based theranostics have emerged as a revolutionary approach in the field of medicine, offering the potential for simultaneous diagnosis and treatment of various diseases.
Pasderhsh Servushan
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