Results 41 to 50 of about 40,969 (293)

Nanozymes in Tumor Theranostics

Frontiers in Oncology, 2021
Nanozymes, a new generation of enzyme mimics, have recently attracted great attention. Nanozymes could catalyze chemical reactions as biological enzymes under physiologically mild conditions with higher-efficiency catalytic activities. Moreover, nanozymes could overcome the shortcomings of natural enzymes, such as easy inactivation, high cost, and low ...
Qiulian Ma, Yanfang Liu, Haitao Zhu, Lirong Zhang, Xiang Liao, Xiang Liao   +5 more
openaire   +3 more sources

COMPARISON OF 68GA-PSMA AND 18F-FDG-PET/CT IN THE ASSESSMENT OF DESMOID TUMORS

Hematology, Transfusion and Cell Therapy
Introduction/Justification: Recently, the tracer Prostate Specific Membrane Antigen (PSMA), which can be labeled with the radioisotopes 68Ga or 18F, has been commercially introduced.
Tobias Luis dos Reis, Kaique Moraes do Amaral, Najua Abou Arab, Maria Emilia Seren Takahashi, José Barreto Campello Carvalheira, Barbara Juarez Amorim, Elba Cristina Sá de Camargo Etchebehere, Mariana da Cunha Lopes de Lima, Allan de Oliveira Santos, Ludmila Santiago Almeida, Eliana Cristina Martins Miranda, Carmen Silvia Passos Lima, Celso Dario Ramos, Sérgio Querino Brunetto, Simone Kuba, NAtália Tobar, Carmino Antonio Souza, Mariana Cortês Caleffi, Mariana Fernandes França Mitre Amorim   +18 more
doaj   +1 more source

Theranostics - a sure cure for cancer after 100 years? [PDF]

Cancer has remained a formidable challenge in medicine and has claimed an enormous number of lives worldwide. Theranostics, combining diagnostic methods with personalized therapeutic approaches, shows huge potential to advance the battle against cancer ...
Castellanos, E. Alejandro, Ronald, John A., Gilad, Assaf A, Witney, Timothy H., Castellanos, E Alejandro, Shuhendler, Adam, Müller, Cristina, Zou, Jianhua, Gilad, Assaf A., Müller, Christina, Ronald, John A, Chen, Xiaoyuan, Witney, Timothy H; id_orcid, Weber, Wolfgang A., Weber, Wolfgang A, Song, Yangmeihui, Matsuura, Naomi, Gilad, Assaf A. (author), Chen, Xiaoyuan (author), Zou, Jianhua (author), Song, Yangmeihui (author), Müller, Cristina (author), Witney, Timothy H. (author), Song, Yangmeihui;Zou, Jianhua;Castellanos, E Alejandro;Matsuura, Naomi;Ronald, John A;Shuhendler, Adam;Weber, Wolfgang A;Gilad, Assaf A;Müller, Cristina;Witney, Timothy H;Chen, Xiaoyuan, Shuhendler, Adam (author), Castellanos, E. Alejandro (author), Weber, Wolfgang A. (author), Matsuura, Naomi (author), Ronald, John A. (author)   +28 more
core   +1 more source

Porphyrins and Phthalocyanines for Theranostics [PDF]

Theranostics, 2012
The field of theranostics is growing rapidly as therapeutic regimes are increasingly being integrated and guided by diagnostic practices such as medical imaging. There is some room for discussion about the general definition of a theranostic agent, if there exists such a definition.
Lovell, Jonathan F., Lo, Pui-Chi
openaire   +2 more sources

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption

Advanced Functional Materials, EarlyView.
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy, Kyle B. Meerbott, Lorenzo Travaglini, Garima S. Dobhal, Artur Sawicki, Marc R. Knecht, Tiffany R. Walsh, Dominic J. Glover   +7 more
wiley   +1 more source

Nuclear Theranostics in Taiwan [PDF]

Nuclear Medicine and Molecular Imaging, 2019
Boron neutron capture therapy and Y-90 radioembolization are emerging therapeutic methods for uncontrolled brain cancers and hepatic cancers, respectively. These advanced radiation therapies are heavily relied on theranostic nuclear medicine imaging before the therapy for the eligibility of patients and the prescribed-dose simulation, as well as the ...
Ko-Han, Lin, Yi-Wei, Chen, Rheun-Chuan, Lee, Ling-Wei, Wang, Fong-In, Chou, Chi-Wei, Chang, Sang-Hue, Yen, Wen-Sheng, Huang   +7 more
openaire   +2 more sources

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Protease‐Activated Theranostic Nanomedicine for Endometriosis Treatment

Advanced Functional Materials, EarlyView.
Endometriosis is a chronic gynecological disorder that affects a substantial proportion of reproductive‐aged women. In this study, we identify aberrant overexpression of matrix metalloproteinase‐9 (MMP‐9) in endometriotic lesions and develop a novel multifunctional nanomedicine that integrates MMP‐9‐targeted therapy, ratiometric photoacoustic (PA ...
Panangattukara Prabhakaran Praveen Kumar, Tae Hoon Kim, Hossein Hosseinirad, Maggie Lee, HyeJoo An, Bruce A. Lessey, Daniel Hanavi, Jung‐Ho Shin, Jae‐Wook Jeong, Taeho Kim   +9 more
wiley   +1 more source

Theranostics in Oncology—Thriving, Now More than Ever

, 2021
Tracing its roots back to the 1940s, theranostics in nuclear oncology has proved successful mainly due to the beneficial effects of image-guided therapeutic concepts for patients afflicted with a variety of different cancers.
Takahiro Higuchi, Steven P. Rowe, Martin G. Pomper, Higuchi, Takahiro, Pomper, Martin G., Rudolf A. Werner, Werner, Rudolf A., Rowe, Steven P.   +7 more
core   +1 more source