Results 101 to 110 of about 5,632,141 (320)

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Epidemiologic, clinical and therapeutic features of primary cutaneous lymphomas in Morocco

JEADV Clinical Practice
Background Few epidemiological studies on primary cutaneous lymphomas are available and related to limited populations. Objectives To characterize the epidemiologic, clinical and therapeutic features of primary cutaneous lymphomas from a global ...
Fouzia Hali, Salma Zakaryaa, Karima Senouci, Zineb Zeggwagh, Fatima Zahra Mernissi, Sara Elloudi, Fatima Zahra Hashas, Said Amal, Ouafa Hocar, Maryem Aboudourib, Awatef Kelati, Inas Chikhaoui, Asmaa Quessar, Soumiya Chiheb   +13 more
doaj   +1 more source

PLANT SPECIES DISTRIBUTION AND THEIR POTENTIAL AS A THERAPEUTIC RESOURCE IN AREA OF THE UNIVERSITI TEKNOLOGI MARA (UiTM) NEGERI SEMBILAN BRANCH KUALA PILAH CAMPUS

Journal of Academia, 2020
Knowledge of species richness and distribution is decisive for the composition of conservation areas. Plants typically contain many bioactive compounds are used for medicinal purposes for several disease treatment.
Rosli Noormi
doaj  

TH9, TH17, and TH22 Cell Subsets and Their Main Cytokine Products in the Pathogenesis of Colorectal Cancer

Frontiers in Oncology, 2019
In recent years, several newly identified T helper (TH) cell subsets, such as TH9, TH17, and TH22 cells, and their respective cytokine products, IL-9, IL-17, and IL-22, have been reported to play critical roles in the development of chronic inflammation ...
Guanglin Cui, Guanglin Cui
doaj   +1 more source

Annona muricata (graviola): toxic or therapeutic [PDF]

, 2008
This paper examines annona muricata (graviola): toxic or ...
Gray, A.I., Hollinshead, J., Jones, L., Jones, P.W., Mohanty, S., Thomas, D., Watson, A.A., Watson, D.G.   +7 more
core  

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Clinical impact of epithelial–mesenchymal transition for cancer therapy

Clinical and Translational Discovery
The epithelial–mesenchymal transition (EMT) represents a pivotal frontier in oncology, playing a central role in the metastatic cascade of cancer—a leading global health challenge.
Nobendu Mukerjee, Sagnik Nag, Bikramjit Bhattacharya, Athanasios Alexiou, Divya Mirgh, Dattatreya Mukherjee, Manab Deb Adhikari, Krishnan Anand, Raman Muthusamy, Sukhamoy Gorai, Nanasaheb Thorat   +10 more
doaj   +1 more source

Therapeutic adjuncts in the endoscopic management of urethral stricture disease: past, present, and future

Frontiers in Urology
Urethral stricture disease is a recurrent and debilitating condition affecting many men of all ages. Management may involve endoscopic or surgical treatment.
Jas Singh
doaj   +1 more source

Direct Percutaneous Needle Puncture and Intrapulmonary Lymphatic Embolization for Treatment of Chylothorax in a Patient with Lymphoma

대한영상의학회지, 2020
Lymphoma is a common cause of nontraumatic chylothorax. Clinical success rates of thoracic duct embolization are lower in patients with nontraumatic chylothorax compared to patients with traumatic chylothorax.
Lee Hwangbo, Hoon Kwon, Chang Ho Jeon, Chang Won Kim   +3 more
doaj   +1 more source