Results 131 to 140 of about 4,916,264 (242)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Proportion of patients in phase 2 oncology trials receiving treatments that are ultimately approved. [PDF]

J Natl Cancer Inst
Ouimet C, Fodor B, Del Paggio JC, Kimmelman J.   +3 more
europepmc   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

HOX gene dysregulation in glioblastoma: a narrative review of current advances. [PDF]

Discov Oncol
Hekim S, Bunda S, Dilibaerguli S, Palihati M, Mamatjan Y.   +4 more
europepmc   +1 more source

Therapeutic Communication From A Constructionist Standpoint [PDF]

, 2012
Gergen, Kenneth J., Gergen, M. M.
core   +2 more sources

Ocular therapeutics [PDF]

Clinical and Experimental Optometry, 2007
Genevieve Napper, Julie Albietz
openaire   +2 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Comparative Analysis of Drug-Induced Sleep Endoscopy With Positive Airway Pressure and Therapeutic Continuous Positive Airway Pressure in the Treatment of Obstructive Sleep Apnea. [PDF]

Laryngoscope Investig Otolaryngol
Sina EM, Molin N, Kaki PC, Ideker H, White S, Boon M, Huntley C.   +6 more
europepmc   +1 more source

Therapeutic Hemapheresis [PDF]

Transfusion Medicine and Hemotherapy, 2012
Mansouri Taleghani, Behrouz, Strasser, Erwin   +1 more
openaire   +4 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source