Results 251 to 260 of about 5,700,393 (345)

Early Treatment With Curative Dose Low-Molecular-Weight Heparin (LMWH) Versus Plasmapheresis in Severe Acute Pancreatitis in Intensive Care: A Comparative Study. [PDF]

Cureus
Yacine A, Mourad O, Soheib Z, Salem H.
europepmc   +1 more source

Cholangiocarcinoma — evolving concepts and therapeutic strategies

Nature Reviews Clinical Oncology, 2018
Sumera Rizvi, Shahid A. Khan, C. Hallemeier, R. Kelley, G. Gores   +4 more
semanticscholar   +1 more source

Progress in Therapeutics [PDF]

The Boston Medical and Surgical Journal, 1902
openaire   +2 more sources

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Infection-sensing minigenome as a novel therapeutic approach against Ebola virus. [PDF]

Mol Ther Nucleic Acids
Wang L, Zell BN, Parrett BJ, Barry MA, Yamaoka S.   +4 more
europepmc   +1 more source

A System of Surgery; Pathological, Diagnostic, Therapeutic, and Operative [PDF]

Samuel D. Gross
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Alternative Lengthening of Telomeres: A Prognostic Paradox in Cancer. [PDF]

Cells
Sung JY.
europepmc   +1 more source

THE THERAPEUTIC EFFECT OF AUREOMYCIN IN EXPERIMENTAL PERITONITIS IN THE DOG II

, 1951
F. B. Schweinburg, Philip Glotzer, Alexander M. Rutenburg, Jacob Fine   +3 more
openalex   +2 more sources