Results 251 to 260 of about 6,381,108 (341)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Erratum: Development of clinical research networks in rural America: Our experience from the Accelerating COVID-19 Therapeutic Interventions and Vaccines-1 trial - CORRIGENDUM. [PDF]

J Clin Transl Sci
Kedar E, Dandachi D, Bryant A, Anstrom KJ, Powderly W.   +4 more
europepmc   +1 more source

Glucagon and α-cells as a novel therapeutic target in the management of diabetes mellitus

, 2013
Н. А. Петунина, Lyubov' Valentinovna Trukhina, Elena Igorevna Sinicyna, М. В. Шестакова   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Potential Targets and Biomarkers of Radionuclide Therapy in Breast Cancer. [PDF]

Cancer Innov
Tan Y, Zeng C, Wang J, Ma F.
europepmc   +1 more source

MESENCHYMAL STEM CELLS AS A THERAPEUTIC STRATEGY FOR MULTIPLE SCLEROSIS: ISSUES AND PERSPECTIVES

, 2017
M. М. Zafranskayа, Д. Б. Нижегородова   +1 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Exosomes: A Comprehensive Exploration of their Beneficial, Detrimental, and Ambiguous Roles in Intercellular Communication and Pathophysiological Processes - Do They Justify the Enthusiasm?

Indian J Dermatol
Kapoor R, Bellani D, Patil R, Gold M, Shome D.   +4 more
europepmc   +1 more source

Exploring MDMA assisted therapy in eating disorders: mechanisms, clinical evidence, and future directions. [PDF]

J Eat Disord
Harkhoe M, Offringa T, Vermetten E.
europepmc   +1 more source