Results 111 to 120 of about 1,630,140 (194)

Safety and Feasibility of Infusing Ex Vivo Expanded Allogeneic Canine Natural Killer Cells for the Treatment of Metastatic Solid Tumours

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Companion canines need advances in therapeutic options for solid tumour malignancies. Natural killer (NK) cell infusions offer a promising treatment modality in canines with solid tumours. Autologous natural killer products are limited by dysfunctional immunity and a manufacturing process that delays care whereas allogeneic NK cells offer the ...
Allison M. Weisnicht, Fernanda Szewc, Monica Moonkyung Cho, Han‐Yun Hannah Cheng, Swetha Ganesh, Lauren Mahoney, Kathryn Fox, Portia R. Smith, Mallery Olsen, Rebecca M. Richards, David M. Vail, Christian M. Capitini   +11 more
wiley   +1 more source

The Italian registry of therapeutic apheresis: Granulocyte-monocyte apheresis in the treatment of inflammatory bowel disease. A multicentric study

, 2011
Leukocytes are thought to play an important role in the pathogenesis of inflammatory bowel diseases; granulocyte-monocyte adsorptive (GMA) apheresis, an extracorporeal technique aimed at removing activated circulating leukocytes from the blood, may ...
Marino Marco, Valeria Saladino, Marco, Marino, Santini, Alessia, Cavallaro, Flaminia, Guidi, Maria Luisa, Valeria D'Ovidio, Alessandro Armuzzi, Giuseppe Repaci, Michele Silla, Armuzzi, Alessandro, Marco Astegiano, Mariabeatrice Principi, Aratari, Annalisa, Annalisa Aratari, Alessia Santini, Daniela Valpiani, Elisabetta Colombo, Maria Luisa Guidi, Astegiano, Marco, Ferraro, Pietro Manuel, Di Leo, Vincenza, Francesco Costa, Chiara Ricci, Flaminia Cavallaro, D'Ovidio, Valeria, Gabriele Riegler, Renata D'Incà, Saladino, Valeria, Giampaolo Bresci, Vincenza Di Leo, Costa, Francesco, Pietro Manuel Ferraro, Roberto Testa, Francesca Calella, Bresci, Giampaolo, Valpiani, Daniela, Riegler, Gabriele, Lecis, Pierenrico, Calella, Francesca, Renato Sablich, Pierenrico Lecis, Testa, Roberto, D'Incã, Renata, Ricci, Chiara, Passalacqua, Stefano, Repaci, Giuseppe, Principi, Mariabeatrice, Stefano Passalacqua, Sablich, Renato, Colombo, Elisabetta, Silla, Michele   +51 more
core   +2 more sources

Predictive biomarkers validation of CD3+ cell apheresis yield in CAR-T manufacturing for diffuse large B-cell lymphoma: a machine learning approach

Scientific Reports
Chimeric antigen receptor (CAR) T-cell therapy has shown significant success in treating diffuse large B-cell lymphoma (DLBCL). The initial step involves collecting autologous CD3+ lymphocytes through apheresis, in which obtaining an adequate CD3+ cell ...
Diego Carbonell, Alejandra Rodríguez-Sosa, Leticia Gómez-Serrano, Ana Pérez-Corral, Gloria Ruano, Marian Galayo, Nuria Panadero, Laura Rufián, Natalia Lorente, Pedro Rodríguez-Barquero, Diego Domingo-Merino, Cristina Muñoz-Martínez, Mi Kwon, Sudipto Das, Ramón García-Sanz, Javier Anguita   +15 more
doaj   +1 more source

Identification of a novel high‐prevalence red blood cell antigen on junctional adhesion molecule‐A defines a new blood group system

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Availability of new technologies has accelerated the pace of blood group discovery, with nine of 48 known systems being discovered in the past 5 years alone, and yet uncharacterized antigens remain. This study involved investigations of samples from a female patient presenting with a moderate strength pan‐reactive ...
Tosti J. Mankelow, Louise A. Tilley, Vanja Karamatic Crew, Benjamin Jones, Marina Izak, Liora Muncher, Vered Yahalom, Nicole M. Thornton   +7 more
wiley   +1 more source

Development of a Uniform Apheresis Case Report Form for Standardized Collection of Apheresis Data

Apheresis is performed worldwide for an increasing number of indications. The development of common data elements (CDE) for apheresis related areas may facilitate conduct of new research, enhance quality initiatives including benchmarking, and improve ...
Balogun, Rasheed A, Wu, Yanyun, Winters, Jeffrey L, Pederson, Thomas, Szczepiorkowski, Zbigniew M, Johnson, Andrew D, Burgstaler, Edwin, Chlebeck, Therese, Nellis, Marianne, Pavenski, Katerina, Armendariz, Tomas, Geile, Kira, Sanchez, Amber P, Collins, Laura, Witt, Volker, Thao, Mai, Schneiderman, Jennifer, Schwartz, Joseph, Zantek, Nicole D, Muthusamy, Amutha, Karam, Oliver, Ramesh, Vidhyalakshmi   +21 more
core   +1 more source

apheresis registry study on Wilson's disease

, 2016
Wilson's disease is a rare autosomal recessive genetic disorder that results in accumulation of copper in the liver, brain, cornea and kidney. Therapeutic plasma exchange (TPE) has been used to remove copper and provide a bridge to liver transplantation.
Kim, Haewon C, Wu, Yanyun, Chisa Yamada, Winters, Jeffrey L, Pham, Huy P, Huy P. Pham, Jeffrey L. Winters, Pagano, Monica B, Morgan, Shanna, Laura Cooling, Jan C. Hofmann, Jennifer Schneiderman, Yanyun Wu, Cooling, Laura, Haewon C. Kim, Monica B. Pagano, Edward C.C. Wong, Schneiderman, Jennifer, Schwartz, Joseph, Shanna Morgan, Hofmann, Jan C, Wong, Edward C C, Yamada, Chisa, Joseph Schwartz   +23 more
core   +1 more source

Continuous agitation induces aggregate formation in cold‐stored platelets during extended storage in platelet additive solution

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Reduced metabolic activity of cold‐stored platelets (CSPs) has led to the assumption that agitation is not required during cold storage. However, guidelines from the Food and Drug Administration state that agitation is ‘optional’ and there is a degree of international variability described in the literature.
Janhavi Mahajan, Pearl Lei, Christopher Roan, Matthew P. Padula, Denese C. Marks, Lacey Johnson   +5 more
wiley   +1 more source

Real-world safety data from the world apheresis association registry for the spectra optia apheresis system

In this study we analyzed 12 years of adverse events, (AE) data from the World Apheresis Association, (WAA) Registry specific to the Spectra Optia Apheresis System.
Mendoza, Sebastian, Skosana, Yona, Vasilache, Ana Maria, Deeren, Dries, Witt, Volker, Glatt, Tanya Nadia, Haubner, Aaron, Bojanic, Ines, Aandahl, Astrid, Vrielink, Hans, Newman, Elizabeth, Gasova, Zdenka, Stegmayr, Bernd, Strineholm, Virginia, Strineholm, Virginia,, Vasilache, Ana-Maria, Bojanic, Ines,, Aandahl, Astrid,, Vrielink, Hans,, Vasilache, Ana-Maria,, Vasilache, Ana Maria,, Stegmayr, Bernd,, Newman, Elizabeth,, Haubner, Aaron,, Deeren, Dries,, Glatt, Tanya Nadia,, Mendoza, Sebastian,, Gasova, Zdenka,, Skosana, Yona,, Witt, Volker,   +29 more
core   +1 more source

Optimization of platelet concentrate inventory management using a simple standardized decision‐support model: A retrospective study from a Regional Blood Center

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Platelet concentrates (PCs) are difficult to manage because of their short shelf‐life and variable clinical demand. The aim of this study was to evaluate the impact of a modified platelet inventory management strategy at a Regional Blood Donation and Treatment Center on product utilization and expiration‐related ...
Anna Lizoń, Monika Marszałek, Wirginia Krzyściak   +2 more
wiley   +1 more source

Principles of Therapeutic Apheresis in Neurological Disease. [PDF]

Transfus Med Hemother, 2023
Strasser E.
europepmc   +1 more source