Results 91 to 100 of about 1,673,090 (317)
Coolmine Therapeutic Communities. Helping people help themselves: annual report 2008. [PDF]
, 2010 Therapeutic Communities (TC) are designed to foster change and positive growth in their clients, emphasising group work and the taking of personal responsibility within a highly structured environment.
core
The treatment of generalised anxiety disorder. A biopsychosocial approach across therapeutic schools
, 2022 The coronavirus pandemic has led many people to experience an existential threat and triggered different forms of coping with this persistent stress situation. The risk for development of a generalised anxiety disorder has increased significantly.
Bättig, Isabelle +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The rise and fall and rise again of the therapeutic community
, 2017 Purpose Therapeutic communities (and many other residential services) have been effectively marginalised in recent years with the increasing popularity of community-based outpatient responses to a variety of social issues including addiction, learning ...
Rowdy Yates, Yates, Rowdy
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
“I’ve Killed My Puppet!” A Relational Psychotherapeutic Approach to Inclusive Classroom Practices
Journal of Curriculum Theorizing, 2019 This article begins with a story called “I’ve killed my puppet” based on an incident that unfolded in the author’s university class, which provides a concrete illustration of the potential of a relational psychotherapeutic approach to inclusion.
Joseph Michael Valente
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2014 Bodil Furnes,1 Gerd Karin Natvig,1,2 Elin Dysvik1 1Department of Health Studies, Faculty of Social Sciences, University of Stavanger, Stavanger, Norway; 2Department of Global Public Health and Primary Care, Faculty of Medicine and Dentistry, University ...
Natvig GK, Dysvik E, Furnes B
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source