Results 101 to 110 of about 2,620,997 (289)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Difficulties in the diagnosis and therapeutic approach in autoimmune polyglandular syndrome type 2. A clinical сase

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2018
Autoimmune polyglandular syndrome is characteri­zed by an immune-mediated destruction of endocrine tissues. The presence of autoimmune diseases of the endocrine system such as type 1 diabetes mellitus, adrenocortical failure and autoimmune thyroid ...
G.F. Gendeleka, A.N. Gendeleka
doaj   +1 more source

Pre-embryo: Therapeutic Approaches

open access: yesAnnals of Medicine, 1993
There are potential interventions in the pre-embryo stage in order to improve the clinical results of assisted reproductive technology, live-birth per cycle of treatment, and to prevent the birth of offspring with genetic aberrations. The following therapeutic measures can be potentially applied to the pre-embryo: improvement of culture conditions, pre-
openaire   +2 more sources

Rat models of autoimmune uveitis [PDF]

open access: yes, 2008
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Diedrichs-Moehring, Maria   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

“I’ve Killed My Puppet!” A Relational Psychotherapeutic Approach to Inclusive Classroom Practices

open access: yesJournal of Curriculum Theorizing, 2019
This article begins with a story called “I’ve killed my puppet” based on an incident that unfolded in the author’s university class, which provides a concrete illustration of the potential of a relational psychotherapeutic approach to inclusion.
Joseph Michael Valente
doaj   +1 more source

Lichen amyloidosus: a new therapeutic approach. [PDF]

open access: yes, 1985
The result of topical treatment by dimethyl sulphoxide (DMSO) in a patient with lichen amyloidosus is reported. Itching improved within five days of therapy. Remarkable flattening of the papules was obtained within two weeks.
Bruno G   +3 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Cognitive-Behavioral Therapy [PDF]

open access: yes, 2015
Cognitive-behavioral therapy (CBT) is the merging of behavioral and cognitive therapies that mostly focuses on working with the client in the present. Although there are many approaches to CBT, there tend to be some common features.
Rice, Robert H.
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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