Results 241 to 250 of about 2,658,769 (310)

Evaluation, Management and Therapeutic Approach of Cardiovascular-Kidney-Metabolic Syndrome: A Multidisciplinary Delphi Expert Consensus. [PDF]

J Clin Med
Orozco-Beltrán D, Quiroga B, Esteban-Fernández A, Lorenzo Almorós A, Bellido V, Benedito Pérez de Inestrosa T, de Haro R, Taboada X, Romero-Vigara JC.   +8 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Lidocaine as a potential anti-seizure therapy for pediatric FIRES: a promising therapeutic approach. [PDF]

Front Pediatr
Yang Y, Wei N, Guan Q, Xie H, Huang X, Ru X, Wu Y, Wang Y, Sang T.   +8 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Harnessing natural sunlight indoors: sensor-regulated therapeutic approach to enhance vitamin D status in humans. [PDF]

Sci Rep
Hakeem MK, Hassan A, Rajendran T, Al-Menhali A, Yasin J, Gariballa S, Shah I.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Electrical vestibular nerve stimulation as a novel therapeutic approach for insomnia: a systematic review and meta-analysis. [PDF]

BMC Psychiatry
Zrineh A, Akwan R, Elsharkawy MM, Mahmoud MAT, Mohammed M, Ghawanmeh EM, AlHabil Y, Mekky J.   +7 more
europepmc   +1 more source

Targeting pyroptosis in inflammatory bowel disease: A potentially effective therapeutic approach. [PDF]

World J Gastroenterol
Dong WW, Liu T, He LX, He WT.
europepmc   +1 more source

Cytoreductive surgery and HIPEC for multicystic peritoneal mesothelioma: therapeutic approach in a rare benign neoplasm. [PDF]

J Surg Case Rep
Aleksandrić G, Trifunović N, Trifunović J, Filipović S, Mitrović N.   +4 more
europepmc   +1 more source

Clazakizumab: A Therapeutic Approach for Patients With Late Antibody-Mediated Rejection. [PDF]

Kidney Int Rep
Jordan SC.
europepmc   +1 more source