Results 41 to 50 of about 1,011,280 (169)

Involvement of SIRT1-mediated aging in liver diseases

Frontiers in Cell and Developmental Biology
Liver disease is a significant global health issue, responsible for millions of deaths annually. Aging, characterized by the gradual decline in cellular and physiological functions, impairs tissue regeneration, increases susceptibility to liver diseases,
Yueming Zhang, Chang Gong, Lina Tao, Jinghui Zhai, Fengwei Huang, Fengwei Huang, Sixi Zhang, Sixi Zhang   +7 more
doaj   +1 more source

C-terminal binding protein-2 triggers CYR61-induced metastatic dissemination of osteosarcoma in a non-hypoxic microenvironment

Journal of Experimental & Clinical Cancer Research
Background Osteosarcoma is the most prevalent cancer-related bone disease diagnosed in the pediatric age group. The rapid development of metastatic lesions and resistance to chemotherapy remain major mechanisms responsible for the failure of treatments ...
Laura Di Patria, Nadia Habel, Robert Olaso, Romain Fernandes, Catherine Brenner, Bojana Stefanovska, Olivia Fromigue   +6 more
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Insights into the glioblastoma tumor microenvironment: current and emerging therapeutic approaches

Frontiers in Pharmacology
Glioblastoma (GB) is an intrusive and recurrent primary brain tumor with low survivability. The heterogeneity of the tumor microenvironment plays a crucial role in the stemness and proliferation of GB.
Dev Kumar Tripathy, Lakshmi Priya Panda, Suryanarayan Biswal, Kalpana Barhwal   +3 more
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The management of developmental stuttering: child psychiatrists’ perspectives

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Stuttering is a communication disorder generally characterized by involuntary disruptions in the flow of speech. Various theories have been offered to explain developmental stuttering, but its causes are not well understood. There is no known
Tümer Türkbay, Ayhan Cöngöloğlu, Müzeyyen Çiyiltepe, İbrahim Durukan, Koray Karabekiroğlu   +4 more
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Yoga and Swimming—A Symbiotic Approach with Positive Impacts on Health and Athletes’ Performance

Applied Sciences
Yoga enhances acceptance, compassion, physicality, mental and emotional awareness, and spiritual benefits through breath techniques, postures, and body locks, while swimming improves flexibility, strength, and body awareness.
Rocsana Bucea-Manea-Țoniș, Andreea Natalia Jureschi (Gheorghe), Luciela Vasile   +2 more
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The Role of PARPs in Inflammation—And Metabolic—Related Diseases: Molecular Mechanisms and Beyond

Cells, 2019
Poly(ADP-ribosyl)ation (PARylation) is an essential post-translational modification catalyzed by poly(ADP-ribose) polymerase (PARP) enzymes. Poly(ADP-ribose) polymerase 1 (PARP1) is a well-characterized member of the PARP family.
Yueshuang Ke, Chenxin Wang, Jiaqi Zhang, Xiyue Zhong, Ruoxi Wang, Xianlu Zeng, Xueqing Ba   +6 more
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The current status of various preclinical therapeutic approaches for tendon repair

Annals of Medicine
Tendons are fibroblastic structures that link muscle and bone. There are two kinds of tendon injuries, including acute and chronic. Each form of injury or deterioration can result in significant pain and loss of tendon function.
Wenqing Liang, Chao Zhou, Yongjun Deng, Lifeng Fu, Jiayi Zhao, Hengguo Long, Wenyi Ming, Jinxiang Shang, Bin Zeng   +8 more
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Enhancing Agricultural Productivity in Dairy Cow Mastitis Management: Innovations in Non-Antibiotic Treatment Technologies

Veterinary Sciences
Dairy mastitis is a common dairy farming disease. It severely affects the health of dairy cows and the quality and yield of dairy products. This paper reviews the main current mastitis treatments and associated bacterial resistance.
Lijie Jiang, Qi Li, Huiqing Liao, Hourong Liu, Zhiqiang Wang   +4 more
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Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis

Frontiers in Pharmacology
BackgroundVitamin B12 deficiency is a widespread condition, particularly among elderly individuals, patients with malabsorption syndromes, and those following plant-based diets.
Marta Mazur, Marta Mazur, Artnora Ndokaj, Claudia Salerno, Claudia Salerno, Jessica Vallone, Roman Ardan, Sabina Bietolini, Florence Carrouel, Aleksandra Wilk, Rachel Sarig, Livia Ottolenghi, Denis Bourgeois   +12 more
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Advancements in vaccine development and therapeutic approaches for severe fever with Thrombocytopenia Syndrome

Frontiers in Cellular and Infection Microbiology
Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by the SFTS virus (SFTSV), is a tick-borne disease that poses a significant public health threat due to its high fatality rate and the lack of effective treatments or vaccines.
Tsenddari Ganbold, Satabdi Acharya, Sunirmal Sheet, Enkhtsatsral Munkhtur, Seong-Tshool Hong   +4 more
doaj   +1 more source