Results 71 to 80 of about 2,295,758 (241)

Australian professional identity in therapeutic recreation : exploring perspectives from the field

open access: yes, 2019
The purpose of this case study was to explore the emerging Australian professional identity in the field of Therapeutic Recreation (TR). Within Australia, the field most closely associated with TR is Diversional Therapy (DT).
Truong, Son (R17154)   +1 more
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Volatile Organic Compound Profiling of Traditional Multi-Herbal Prescriptions for Chemical Differentiation and Ethnopharmacological Insights

open access: yesSeparations
Traditional herbal prescriptions composed of multiple botanicals remain central to ethnopharmacological practice; however, their chemical basis and classification remain poorly understood.
Sumin Seo   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Managing across knowledge boundaries

open access: yes, 2017
This chapter discusses the implications of knowledge specialization in relation to five types of knowledge boundaries (individual, domain-specific, task-oriented, spatial, and temporal), and mechanisms that potentially could be used to bridge these ...
Tell, Fredrik,
core  

Importance of low-angle grain boundaries in YBa2Cu3O7-delta coated conductors [PDF]

open access: yes, 2008
Over the past ten years the perception of grain boundaries in YBa2Cu3O7−δ conductors has changed greatly. They are now not a problem to be eliminated, but an inevitable and potentially favourable part of the material.
N A Rutter, J H Durrell
core   +2 more sources

Chitosan Micro/Nanocapsules in Action: Linking Design, Production, and Therapeutic Application

open access: yesMolecules
pH sensitivity of chitosan allows for precise phase transitions in acidic environments, controlling swelling and shrinking, making chitosan suitable for drug delivery systems.
Yaride Pérez-Pacheco   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

“Finding my voice again” - women’s experiences of psychological therapy in perinatal secondary care settings: a qualitative study

open access: yesFrontiers in Psychiatry
IntroductionAlthough women often experience mental health comorbidities in the perinatal period, the evidence-base for psychological therapy across diagnostic boundaries in the perinatal period remains limited.
Jayne O’Brien   +5 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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