Results 91 to 100 of about 1,472,669 (399)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura +5 more
wiley +1 more source
Optical Biosensors for Therapeutic Drug Monitoring
Biosensors, 2019 Therapeutic drug monitoring (TDM) is a fundamental tool when administering drugs that have a limited dosage or high toxicity, which could endanger the lives of patients.
Vivian Garzón +4 more
doaj +1 more source
Therapeutic Drug Monitoring in Inflammatory Bowel Disease
Journal of Coloproctology, 2023 Inflammatory bowel disease (IBD) is a problem that directly affects the quality of life of patients suffering from this condition. Monitoring the serum level of infliximab (IFX) (TDM) is an important tool for guiding therapeutic decisions in IBD patients.
Manoel Alvaro de Freitas Lins Neto +6 more
doaj +1 more source
Therapeutic drug monitoring of cytotoxic drugs [PDF]
British Journal of Clinical Pharmacology, 2001 Therapeutic drug monitoring is not routinely used for cytotoxic agents. There are several reasons, but one major drawback is the lack of established therapeutic concentration ranges. Combination chemotherapy makes the establishment of therapeutic ranges for individual drugs difficult, the concentration‐effect relationship for a single drug may not be ...
openaire +3 more sources
Antiepileptic Drug Level Monitoring [PDF]
, 2008 Routine monitoring of antiepileptic drug levels does not alter seizure or side effect rates. (Strength of Recommendation [SOR]: B, based on a single randomized controlled trial [RCT] with less than 80 percent follow-up).
Malaty, Wail, Stigleman, Sue
core
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Formulation Approaches for Optimizing Omeprazole Stability in Oral Liquid Dosage Forms
PharmaceuticsBackground/Objectives: This study aimed to evaluate the degradation of omeprazole suspension under various pH conditions and to propose recommendations for preparing compounded suspensions.
Urszula Adamiak-Giera +6 more
doaj +1 more source
Antibiotics, 2021 Isavuconazole (ISZ) is used in the treatment of aspergillosis and mucormycosis. The purpose of this study was to evaluate the therapeutic drug monitoring (TDM) of ISZ samples from a clinical setting performed at Statens Serum Institut. Materials/methods:
Malene Risum +5 more
doaj +1 more source
Measuring mental health in criminology research: Lessons from the Drug Use Monitoring in Australia program [PDF]
, 2013 Poor mental health among people in the Australian criminal justice system is increasingly being identified and targeted for remediation. This is evidenced by Australian and international governments establishing specialist services for prisoners with ...
Lubica Forsythe
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source