Results 191 to 200 of about 1,472,669 (399)

Medication burden and clustering in people living with HIV undergoing therapeutic drug monitoring [PDF]

open access: bronze, 2021
Andrea Calcagno   +10 more
openalex   +1 more source

Recidivism in Alaska [PDF]

open access: yes, 2008
Recidivism data are a tool that can help policymakers determine how effectively a criminal justice system is working to protect the public. Such data can help answer whether the current system is appropriate, whether alternative methods could provide ...
Carns, Teresa W.
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Bio-analytical Assay Methods used in Therapeutic Drug Monitoring of Antiretroviral Drugs-A Review

open access: bronze, 2018
Nitin B. Charbe   +5 more
openalex   +2 more sources

628. Utilizing Cefepime Therapeutic Drug Monitoring for Patients at Risk of or Exhibiting Signs of Neurotoxicity [PDF]

open access: gold, 2022
Joanna Au   +5 more
openalex   +1 more source

Comparison of patient outcomes in a pharmacist-led outpatient parenteral antimicrobial therapy program [PDF]

open access: yes, 2019
Purpose: Outpatient parenteral antimicrobial therapy (OPAT) is a therapeutic option meant to conserve healthcare resources when treating infections requiring the administration of IV antibiotics over a prolonged treatment course.
Howe, Zachary
core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Evaluation of theophylline therapeutic drug monitoring service

open access: yesZdravniški Vestnik, 2015
BackgroundTherapeutic monitoring of theophylline serum levels is required due to its narrow therapeutic range and marked interindividual pharmacokinetic variability.
Neža Rugelj   +5 more
doaj  

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