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Physiologically Based Pharmacokinetic Modeling to Predict Lamotrigine Exposure in Special Populations to Facilitate Therapeutic Drug Monitoring and Guide Dosing Regimens. [PDF]

Pharmaceuticals (Basel)
Li JC, Miao CF, Lei Y, Liu AL.
europepmc   +1 more source

Optimization of Preemptive Therapy for Cytomegalovirus Infections With Valganciclovir Based on Therapeutic Drug Monitoring: Protocol for a Phase II, Single-Center, Single-Arm Trial.

JMIR Res Protoc
Tamura N, Itohara K, Ueda Y, Kitahiro Y, Yamamoto K, Omura T, Sakane T, Saegusa J, Yano I.   +8 more
europepmc   +1 more source

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Therapeutic Drug Monitoring of Antibiotics: Defining the Therapeutic Range

Therapeutic Drug Monitoring, 2021
Purpose: In the present narrative review, the authors aimed to discuss the relationship between the pharmacokinetic/pharmacodynamic (PK/PD) of antibiotics and clinical response (including efficacy and toxicity).
M. Abdul-Aziz, Kara Brady, M. Cotta, J. Roberts   +3 more
semanticscholar   +1 more source

A guide to therapeutic drug monitoring of β‐lactam antibiotics

Pharmacotherapy, 2021
Therapeutic drug monitoring (TDM) opens the door to personalized medicine, yet it is infrequently applied to β‐lactam antibiotics, one of the most commonly prescribed drug classes in the hospital setting.
A. Fratoni, D. Nicolau, J. Kuti
semanticscholar   +1 more source

Therapeutic Drug Monitoring Can Improve Linezolid Dosing Regimens in Current Clinical Practice: A Review of Linezolid Pharmacokinetics and Pharmacodynamics.

Therapeutic Drug Monitoring, 2020
Linezolid is an antibiotic used to treat infections caused by drug-resistant gram-positive organisms, including vancomycin-resistant Enterococcus faecium, multi-drug resistant Streptococcus pneumoniae, and methicillin-resistant Staphylococcus aureus. The
G. Rao, Robyn Konicki, D. Cattaneo, J. Alffenaar, D. Marriott, M. Neely   +5 more
semanticscholar   +1 more source