Results 91 to 100 of about 5,258 (286)

Dosimetric Study Of Genipin Gelatin-Chemical Additives Polymer Gel Using 6 Mv And 10 Mv Therapeutic Facilities [PDF]

open access: yes, 2015
Nanopartikel emas AuNPs dari bahan bernombor atom (Z) tinggi, garam bukan organik dan glukosa telah digunakan dalam kajian ini untuk meningkatkan sifat-sifat fizikal dan radiologi genipin dosimeter gel untuk aplikasi klinikal yang berbeza.
Aljarrah, Amer Mahmoud Mohammad
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

THE COMMON FACTORS THEORY: EXPLORING THE EVIDENCE AND CRITIQUES OF THE COMMON FACTORS THEORY. AN ARGUMENT FOR TECHNICAL ECCLETICISM

open access: yes
For decades the clinical psychology community has been grappling with a key question: what causal mechanisms of changes result in improvements for clients.
Madeleine Coad (19670101)
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Evaluation of dosimetric characteristics of diodes and ionization chambers in small megavoltage photon field dosimetry

open access: yes, 2018
Background: Modern radiation therapy such as intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) has resulted in using small therapeutic photon beams.
Shanei, Ahmad   +2 more
core   +1 more source

Aquisição de medicamentos genéricos em município de médio porte Adquisición de medicamentos genéricos en municipio de medio porte Procurement of generic medicines in a medium size municipality

open access: yesRevista de Saúde Pública, 2011
OBJETIVO: Analisar o impacto financeiro da aquisição de medicamentos com a exigência da apresentação de testes de biodisponibilidade e/ou bioequivalência para o componente da Assistência Farmacêutica Básica.
Gabriela Bevilacqua   +2 more
doaj  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Generic Medicines : Perceptions Of Physicians, Pharmacists, Consumers, Final Year Medical And Pharmacy Students In Iraq [PDF]

open access: yes, 2011
Generic medicines provide an opportunity for major savings in health care expenditure to both government and consumers Within this context, no studies have been conducted in Iraq regarding the perceptions held by physicians, pharmacists, consumers and ...
Al-Sharrad, Adheed Khalid Sharrad
core  

Home - About - Disclaimer - Privacy