Results 81 to 90 of about 1,519,681 (281)

Therapeutic equivalence of inhaled salbutamol [PDF]

Thorax, 2000
The meta-analysis by Hughes et al was hindered by difficulties in comparing trials that were often flawed and of varied design.1 The authors correctly pointed out that, in most of the studies, the use of equivalence as the null hypothesis was invalid. In addition, all but two of the studies looked at the bronchodilator effects in the presence of basal ...
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Statistical Analysis: High School Equivalency Program [PDF]

, 1977
This report contains statistics regarding the High School Equivalency Program in the United States, 1972 ...
United States Department of Education
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Multisource drug policies in Latin America: survey of 10 countries

Bulletin of the World Health Organization, 2005
Essential drug lists and generic drug policies have been promoted as strategies to improve access to pharmaceuticals and control their rapidly escalating costs.
Homedes Núria, Ugalde Antonio
doaj  

Development of the Japanese version of the 30‐item Mystical Experience Questionnaire

Neuropsychopharmacology Reports
Introduction Psychedelics have garnered increased attention as potential therapeutic options for various mental illnesses. Previous studies reported that psychedelics cause psychoactive effects through mystical experiences induced by these substances ...
Kengo Yonezawa, Hideaki Tani, Shinichiro Nakajima, Hiroyuki Uchida   +3 more
doaj   +1 more source

Generic antihypertensive medications with therapeutic interchangeability requirements [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2019
Señor Editor: La hipertensión arterial (HTA) es el factor de riesgo cardiovascular más prevalente y causa de muerte prematura a nivel mundial. Según Organización Mundial de la Salud (OMS) la HTA provoca 7,5 millones de muertes al año, que equivale al ...
Giulianna Gamero-Vega, Percy Ocampo-Rujel   +1 more
doaj  

Australian professional identity in therapeutic recreation : exploring perspectives from the field

, 2019
The purpose of this case study was to explore the emerging Australian professional identity in the field of Therapeutic Recreation (TR). Within Australia, the field most closely associated with TR is Diversional Therapy (DT).
Truong, Son (R17154), Peel, Nicole (R18401)   +1 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A multi-center interventional study to assess pharmacokinetics, effectiveness, and tolerability of prolonged-release tacrolimus after pediatric kidney transplantation: study protocol for a prospective, open-label, randomized, two-phase, two-sequence, single dose, crossover, phase III b trial

Frontiers in Nephrology
BackgroundTacrolimus, a calcineurin inhibitor (CNI), is currently the first-line immunosuppressive agent in kidney transplantation. The therapeutic index of tacrolimus is narrow due to due to the substantial impact of minor variations in drug ...
Sinem Karaterzi, Burkhard Tönshoff, Thurid Ahlenstiel-Grunow, Maral Baghai, Maral Baghai, Bodo Beck, Anja Büscher, Lisa Eifler, Thomas Giese, Susanne Lezius, Carsten Müller, Jun Oh, Antonia Zapf, Lutz T. Weber, Lars Pape   +14 more
doaj   +1 more source