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Enhancement of gemcitabine toxicity and specificity through PI3K/Akt/Nrf2 pathway inhibition in pancreatic cancer. [PDF]
Front PharmacolChen YS, O'Hagan S, Day PJR.
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Guillain-Barré Syndrome: Progress in Diagnosis, Biomarkers, Neuroimaging and Management. [PDF]
Immunotargets TherFreiha J, Min YG, Osman C, Rajabally YA.
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Exploring the nonlinear relationship between serum uric acid to high-density lipoprotein cholesterol ratio and obesity in older adults: a cross-sectional study. [PDF]
Front Public HealthWang F +5 more
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Development and validation of a bioanalytical method to quantify povorcitinib in human skin with clinical application. [PDF]
BioanalysisXun Z, Zhang L, Wen H, McGee R, Wang P.
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On Therapeutic Equivalency and the Antisubstitution Laws
JAMA: The Journal of the American Medical Association, 1973 The comparative bioavailability of a drug in similarly formulated preparations is becoming a subject of considerable interest and importance to the physician. Drugs usually are not administered as pure compounds but are combined with materials such as binders, excipients, lubricants, preservatives, or other substances generally considered to be ...
Donald O. Schiffman
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Establishing Therapeutic Equivalency
Archives of Internal Medicine, 1986 Allan S. Detsky
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The therapeutic equivalence of complex drugs
Regulatory Toxicology and Pharmacology, 2011When the patent of a small molecule drug expires generics may be introduced. They are considered therapeutically equivalent once pharmaceutical equivalence (i.e. identical active substances) and bioequivalence (i.e. comparable pharmacokinetics) have been established in a cross-over volunteer study.
Schellekens, Huub +5 more
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