Results 51 to 60 of about 1,519,681 (281)

Comparison of Three Different Regimens of Oral Azithromycin in the Treatment of Acne Vulgaris

open access: yesمجله دانشکده پزشکی اصفهان, 2012
Background: Acne vulgaris is a common skin disease that involves pilosebaceous units. Orally administered antibiotics are the most widely systemic therapeutics prescribed for the treatment of moderate to severe acne vulgaris.
Farahnaz Fatemi Naeini, Hooman Akrami
doaj  

Comparison of the Multiattribute Utility Instruments EQ-5D and SF-6D in a Europe-Wide Population-Based Cohort of Patients with Inflammatory Bowel Disease 10 Years after Diagnosis

open access: yesGastroenterology Research and Practice, 2016
Background. The treatment of chronic inflammatory bowel disease (IBD) is costly, and limited resources call for analyses of the cost effectiveness of therapeutic interventions.
Gert Huppertz-Hauss   +9 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Leveraging PET to image folate receptor α therapy of an antibody-drug conjugate

open access: yesEJNMMI Research, 2018
Background The folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), IMGN853, shows great antitumor activity against FRα-expressing tumors in vivo, but patient selection and consequently therapy outcome are based on immunohistochemistry.
Christian Brand   +8 more
doaj   +1 more source

Applying the interaction equivalency theorem to online courses in a large organization [PDF]

open access: yes, 2014
Finding effective ways of designing online courses is a priority for corporate organizations. The interaction equivalency theorem states that meaningful learning can be achieved as long as courses are designed with at least a high level of one of three ...
Armellini, Alejandro   +2 more
core   +1 more source

On the Macedonian equivalency of English plant idioms [PDF]

open access: yes, 2011
This paper focuses on the analysis of English plant idioms and their Macedonian counterparts establishing the level of equivalency, or non-equivalency in some cases.
Ivanovska, Biljana, Biljana Ivanovska
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Policy regarding 24-Hour Equivalency Program [PDF]

open access: yes, 1974
A student accepted into the Twenty-Four Hour Equivalency Program shall not be eligible to engage in organized intercollegiate extra-curricular activities until he/she successfully completes 24 hours of an academic program approved by the Equivalency ...
The College at Brockport, College Senate
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Flaws and Future of Islet Volume Measurements

open access: yesCell Transplantation, 2018
When working with isolated islet preparations, measuring the volume of tissue is not a trivial matter. Islets come in a large range of sizes and are often contaminated with exocrine tissue.
Han-Hung Huang   +2 more
doaj   +1 more source

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