Results 221 to 230 of about 2,567,854 (328)

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Unveiling Immune System Perturbations in Early Development Through Zebrafish Models of NADHX Repair Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The vital cofactors NADH and NADPH are prone to hydration, forming hydroxylated redox‐inactive derivatives (NADHX and NADPHX) in cells. These damaged metabolites are repaired by two highly conserved enzymes, an NAD(P)HX dehydratase (NAXD) and an NAD(P)HX epimerase (NAXE).
Myrto Patraskaki, Najmesadat Seyedkatouli, Lisa Schlicker, Marc O. Warmoes, Maria Lorena Cordero‐Maldonado, Ursula Heins‐Marroquin, Carole L. Linster   +6 more
wiley   +1 more source

Predictive model for feeding intolerance in neonates with hypoxic ischemic encephalopathy during therapeutic hypothermia. [PDF]

Sci Rep
Shui Z, Liu Y, Duan H, Sun Q, He H, He H, Wang J, Yin H.   +7 more
europepmc   +1 more source

Mitochondrial Dysfunction in Propionic Acidemia: A Case‐Report and Review of the Literature

JIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Propionic acidemia is an inborn error of metabolism involving an enzymatic defect of propionyl‐CoA carboxylase that results in the build‐up of toxic metabolites which can induce metabolic decompensation. Secondary mitochondrial dysfunction in propionic acidemia has been commonly recognized; however, its clinical presentation and management are
Brandon K. Walther, Brittany M. Murray, Poornima Pandiyan, Randall Ray, Laura Yeoh, Amy Kritzer   +5 more
wiley   +1 more source

Therapeutic hypothermia with rapid thin liquid convection is safe and feasible in acute ischemic stroke patients: the SISCO pilot study. [PDF]

Front Neurol
Salerian JA, Schock RB, Schirmer CM, Sen S, Martin-Schild S, Goren O, Kupas DF, Freedman RJ, Aysenne A.   +8 more
europepmc   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Five‐Minute Apgar Scores and Its Prognostic Value for Mortality and Severe Morbidity in Very Preterm Infants: A Multinational Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 649-659, March 2026.
ABSTRACT Objective To examine associations between a 5‐min Apgar score < 7 and severe neonatal outcomes in very preterm (VPT) infants and how results are impacted by variations in assigning Apgar scores within an international context. Design Prospective observational population‐based cohort study.
Harald Ehrhardt, Soodabeh Behboodi, Rolf F. Maier, Adrien M. Aubert, Ulrika Åden, Elizabeth S. Draper, Anna Gudmundsdottir, Veronica Siljehav, Heili Varendi, Tom Weber, Michael Zemlin, Jennifer Zeitlin, on behalf of the EPICE/SHIPS Research Group, J. Lebeer, P. Van Reempts, E. Bruneel, E. Cloet, A. Oostra, E. Ortibus, I. Sarrechia, K. Boerch, L. Huusom, P. Pedersen, T. Weber, A. Hasselager, L. Toome, H. Varendi, M. Männamaa, P. Y. Ancel, A. Burguet, P. H. Jarreau, V. Pierrat, P. Truffert, R. F. Maier, M. Zemlin, B. Misselwitz, S. Schmidt, L. Wohlers, M. Cuttini, D. Di Lallo, G. Ancora, D. Baronciani, V. Carnielli, I. Croci, G. Faldella, F. Ferrari, F. Franco, G. Gargano, A. van Heijst, C. Koopman‐Esseboom, J. Gadzinowski, J. Mazela, A. Montgomery, T. Pikuła, H. Barros, R. Costa, L. Mendes Graça, M. do Céu Machado, C. Rodrigues, T. Rodrigues, U. Aden, A. K. Edstedt Bonamy, M. Norman, E. S. Draper, E. M. Boyle, A. Fenton, S. J. Johnson, B. N. Manktelow, D. W. A. Milligan, S. Mader, N. Thiele, J. Walz, S. Petrou, J. Zeitlin, M. Bonet, C. Bonnet, R. El Raffei, A. Piedvache, A. V. Seppanen, A. M. Aubert   +79 more
wiley   +1 more source

Urinary metabolome at birth in patients with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia and long-term neurodevelopmental outcomes: a 7-year follow up. [PDF]

J Transl Med
Ancona C, Valerio E, Mainini N, Favali A, D'Errico I, Lasagni C, Stocchero M, Pirillo P, Giordano G, Sartori S, Baraldi E.   +10 more
europepmc   +1 more source

Measurement and management of adult blood pressure in the peri‐operative period: updated guidelines from the Association of Anaesthetists and the British and Irish Hypertension Society

Anaesthesia, Volume 81, Issue 3, Page 402-414, March 2026.
Summary Introduction Maintaining stable blood pressure during surgery is a key responsibility of anaesthetists. Peri‐operative omission and reintroduction of antihypertensive drugs, general anaesthesia, neuraxial and regional techniques can all cause significant fluctuations in blood pressure, particularly in patients with hypertension. Since the first
Terry McCormack, Alex Wickham, Sinéad T. J. McDonagh, Matthew D. Wiles, Luca Faconti, Rachael Brooks, Simon G. Anderson, Andrew Hartle   +7 more
wiley   +1 more source

Combined effects of <b>β</b>-hydroxybutyrate and therapeutic hypothermia in a neonatal hypoxia-ischemia model. [PDF]

J Cereb Blood Flow Metab
Fabres RB, Carvalho AVS, Silva Alós DKD, Machado DN, Spies FF, Cardoso DS, Vido MFC, Martini APR, Mattos MM, Antunes BP, Hoeper E, Venturin GT, Greggio S, Takada SH, Drobyshevsky A, de Fraga LS, Netto CA.   +16 more
europepmc   +1 more source