Results 21 to 30 of about 1,560,342 (283)

Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling [PDF]

, 2009
Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Meybohm, Patrick, Zitta, Karina, Matthias Gruenewald, Nguyen Tran, Grünewald, Matthias Lars, Martin Albrecht, Koch, Alexander, Karina Zitta, Lucius, Ralph, Scholz, Jens, Kai D Zacharowski, Patrick Meybohm, Bein, Berthold Helmut, Berthold Bein, Albrecht, Martin, Ralph Lucius, Jens Scholz, Alexander Koch, Zacharowski, Kai, Tran, Thi Hoai Nguyen   +19 more
core   +2 more sources

A novel ECG-biomarker for cardiac arrest during hypothermia

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2020
Background Treatment of arrhythmias evoked by accidental or therapeutic hypothermia and rewarming remains challenging. We aim to find an ECG-biomarker that can predict ventricular arrhythmias at temperatures occurring in therapeutic and accidental ...
Erik Sveberg Dietrichs, Torkjel Tveita, Rachel Myles, Godfrey Smith   +3 more
doaj   +1 more source

Long-chain omega-3 polyunsaturated fatty acids are reduced in neonates with substantial brain injury undergoing therapeutic hypothermia after hypoxic–ischemic encephalopathy

Frontiers in Neurology, 2023
Hypoxic–ischemic encephalopathy (HIE) is a major cause of neonatal morbidity and mortality. Although therapeutic hypothermia is an effective treatment, substantial chronic neurological impairment often persists.
Simon C. Dyall, Isabell Nessel, Jennine A. Sharpe, Ping K. Yip, Adina T. Michael-Titus, Divyen K. Shah, Divyen K. Shah   +6 more
doaj   +1 more source

Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation [PDF]

, 2010
Introduction: Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion in-jury.
Meybohm, Patrick, Zitta, Karina, Grünewald, Matthias Lars, Albrecht, Martin, Zacharowski, Kai, Lucius, Ralph, Hensler, Johannes, Bein, Berthold, Fösel, Nikola   +8 more
core   +1 more source

Overview of Therapeutic Hypothermia [PDF]

Current Treatment Options in Neurology, 2012
Therapeutic hypothermia has proven neuroprotective effects in global cerebral ischemia. Indications for hypothermia induction include cardiac arrest and neonatal asphyxia. The two general methods of induced hypothermia are either surface cooling or endovascular cooling.
Shlee S, Song, Patrick D, Lyden
openaire   +2 more sources

Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocol [PDF]

, 2011
Background: There is now convincing evidence that in industrialized countries therapeutic hypothermia for perinatal asphyxial encephalopathy increases survival with normal neurological function. However, the greatest burden of perinatal asphyxia falls in
Allen, Elizabeth, Allen Elizabeth, Cornelia F Hagmann, Jacobs Ian, Hagmann, Cornelia F., Nakakeeto Margaret, Elbourne, Diana, Jacobs, Ian, Ian Jacobs, Costello, Anthony, Frances Cowan, Acolet Dominique, Nicola J Robertson, Acolet, Dominique, Anthony Costello, Cowan Frances, Cowan, Frances, Acolet, D, Elbourne, D, Nyombi, Natasha, Robertson, Nicola J., Hagmann Cornelia F, Dominique Acolet, Robertson Nicola J, Robertson, NJ, Diana Elbourne, Margaret Nakakeeto, Nyombi Natasha, Cowan, F, Jacobs, I, Costello, A, Nakakeeto, Margaret, Robertson, Nicola J, Elbourne Diana, Hagmann, Cornelia F, Nakakeeto, M, Elizabeth Allen, Hagmann, CF, Nyombi, N, Allen, E, Costello Anthony, Natasha Nyombi   +41 more
core   +2 more sources

Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model

Mediators of Inflammation, 2015
Background. The deterioration of hemodynamics instantly endangers the patients’ life after polytrauma. As accidental hypothermia frequently occurs in polytrauma, therapeutic hypothermia still displays an ambivalent role as the impact on the ...
Matthias Weuster, Philipp Mommsen, Roman Pfeifer, Juliane Mohr, Steffen Ruchholtz, Sascha Flohé, Matthias Fröhlich, Claudia Keibl, Andreas Seekamp, Martijn van Griensven, Ingo Witte   +10 more
doaj   +1 more source

Hipotermia terapêutica em pacientes com asfixia neonatal - Estudo transversal em UTI neonatal do Sul do Brasil

Residência Pediátrica, 2023
INTRODUCTION: Neonatal asphyxia causes a large part of infant deaths, especially during the perinatal period. In addition to the high mortality rate, it is also responsible for the majority of brain disabilities in patients born at term.
Mariana Martins Denicol, Marcelo de Freitas Calegari, Cátia Rejane Soares de Soares, Valéria Raymundo Fonteles Ritter   +3 more
doaj   +1 more source

An inspection of therapeutic hypothermia preceding coronary reperfusion in patients with a cardiogenic shock complicating anterior ST-segment elevation myocardial infarction

International Journal of Cardiology: Heart & Vasculature, 2015
Background: We retrospectively investigated our hypothesis that pre-percutaneous coronary intervention (PCI) procedural therapeutic hypothermia may have clinical advantages in patients with a profound cardiogenic shock complicating anterior ST-segment ...
Makoto Suzuki, Atsushi Seki, Itaru Takamisawa, Tetsuya Tobaru, Morimasa Takayama, Tetsuya Sumiyoshi, Hitonobu Tomoike   +6 more
doaj   +1 more source

Dexmedetomidine for Sedation of Neonates with HIE Undergoing Therapeutic Hypothermia: A Single-Center Experience

American Journal of Perinatology Reports, 2018
Hypoxic-ischemic encephalopathy (HIE) is a significant cause of morbidity and mortality in neonates. Therapeutic hypothermia reduces the risk of death or disability.
Keliana O'Mara, Michael D. Weiss
doaj   +1 more source