Results 51 to 60 of about 2,567,854 (328)

Preemptive Morphine During Therapeutic Hypothermia After Neonatal Encephalopathy: A Secondary Analysis

open access: yesTherapeutic Hypothermia and Temperature Management, 2020
Although therapeutic hypothermia (TH) improves outcomes after neonatal encephalopathy (NE), the safety and efficacy of preemptive opioid sedation during cooling therapy is unclear.
N. Liow   +9 more
semanticscholar   +1 more source

Review of the Clinical Evidence and Controversies in Therapeutic Hypothermia for Survivors of Sudden Cardiac Death

open access: yesProceedings of Singapore Healthcare, 2015
Sudden cardiac arrest constitutes a major public health burden in both developed and developing countries. In those successfully resuscitated from cardiac arrest, subsequent mortality is still high (∼75%) and is due to a combination of ischaemia and ...
Eric Tien Siang Lim MBBChir, MRCP   +5 more
doaj   +1 more source

Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy. [PDF]

open access: yes, 2017
Global patterns of brain injury correlate with motor, cognitive, and language outcomes in survivors of neonatal encephalopathy (NE). However, it is still unclear whether local changes in brain structure predict specific deficits.
Barkovich, A James   +9 more
core   +2 more sources

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]

open access: yes, 2014
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M   +5 more
core   +2 more sources

No neuroprotective effect of therapeutic hypothermia following lipopolysaccharide-sensitized hypoxia-ischemia: a newborn piglet study

open access: yesFrontiers in Pediatrics, 2023
IntroductionTherapeutic hypothermia is the only proven neuroprotective treatment for hypoxic-ischemic encephalopathy. However, studies have questioned whether therapeutic hypothermia may benefit newborns subjected to infection or inflammation before a ...
Mads Andersen   +17 more
doaj   +1 more source

A New Vision for Therapeutic Hypothermia in the Era of Targeted Temperature Management: A Speculative Synthesis

open access: yesTherapeutic Hypothermia and Temperature Management, 2019
Three decades of animal studies have reproducibly shown that hypothermia is profoundly cerebroprotective during or after a central nervous system (CNS) insult.
Travis C. Jackson, P. Kochanek
semanticscholar   +1 more source

Therapeutic Hypothermia Improves Hind Limb Motor Outcome and Attenuates Oxidative Stress and Neuronal Damage in the Lumbar Spinal Cord Following Cardiac Arrest

open access: yesAntioxidants, 2020
Hypothermia enhances outcomes of patients after resuscitation after cardiac arrest (CA). However, the underlying mechanism is not fully understood.
J. Ahn   +14 more
semanticscholar   +1 more source

Neuroprotective Properties of Xenon. [PDF]

open access: yes, 2020
Xenon is a rare noble gas that was introduced into clinical practice more than 70 years ago. Xenon's clinical properties are predicated by its ability to fit into preformed cavities of macromolecules thereby altering their biological functions.
Laitio, Timo, Maze, Mervyn
core  

Neonatal Thrombocytopenia after Perinatal Asphyxia Treated with Hypothermia: A Retrospective Case Control Study

open access: yesInternational Journal of Pediatrics, 2014
Our objective was to estimate the effect of therapeutic hypothermia on platelet count in neonates after perinatal asphyxia. We performed a retrospective case control study of all (near-) term neonates with perinatal asphyxia admitted between 2004 and ...
N. Boutaybi   +6 more
doaj   +1 more source

Updates on Selective Brain Hypothermia: Studies From Bench Work to Clinical Trials

open access: yesFrontiers in Neurology, 2022
Thrombectomy or thrombolysis are the current standards of care for acute ischemic stroke (AIS), however, due to time constraints regarding operations and a multitude of contraindications, AIS remains one of the leading causes of death and chronic ...
Xiaoyu Wang   +8 more
doaj   +1 more source

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