Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis. [PDF]
BackgroundTuberculosis (TB) is the leading cause of death from an infectious pathogen worldwide and the most prevalent opportunistic infection in people living with HIV.
Bacchetti, Peter +6 more
core +1 more source
Abstract A 10‐month‐old, neutered, male domestic shorthair cat with outdoor access was presented with a thoracic wound, severe respiratory distress, cachexia, dehydration and pleural effusion. Imaging confirmed bilateral pyothorax. Haematology showed marked neutrophilia with left shift, mild anaemia, thrombocytopenia and lymphocytosis.
Hugo Martínez‐Jarquin +5 more
wiley +1 more source
Renin-angiotensin system activation correlates with microvascular dysfunction in a prospective cohort study of clinical sepsis [PDF]
Microvascular dysregulation characterized by hyporesponsive vessels and heterogeneous bloodflow is implicated in the pathogenesis of organ failure in sepsis.
Kevin C Doerschug +3 more
core +2 more sources
Creative and Adaptive Solutions for Early Diagnosis of Sickle Cell Disease in Sub‐Saharan Africa
ABSTRACT Many of the children with sickle cell disease born in sub‐Saharan Africa remain undiagnosed and untreated. Increasing capacity and infrastructure to support diagnostic and screening programs in high income countries have enabled near universal survival into adulthood.
Luke R. Smart +2 more
wiley +1 more source
Health-related quality of life and depression among participants in the Sjögren's International Collaborative Clinical Alliance registry. [PDF]
ObjectiveTo examine health-related quality of life (HRQoL) and depression among participants in an international Sjögren's syndrome (SS) registry, comparing those with and without SS.MethodsCross-sectional study of participants in the Sjögren's ...
Chou, Annie +5 more
core +1 more source
Genome sequencing helped find answers for 1 in 5 children with rare conditions in an outpatient study looking at hybrid genetic care delivery. Families who chose testing themselves had the highest diagnostic yield, showing that self‐referral may be a helpful way to improve access to genetic care.
Kristin Theobald +10 more
wiley +1 more source
RECRUITMENT OF PATIENTS WITH HEREDITARY HAEMOCHROMATOSIS AS BLOOD DONORS
Background. Hereditary haemochromatosis is the most common inherited disorder in white persons with prevalence of about 1 in 200. Therapeutic phlebotomy is an effective treatment for the disease and prevents its sequele.
Marko Cukjati, Dragoslav Domanovič
doaj
Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers
What's new? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam +18 more
wiley +1 more source
Growth hormone (GH)‐induced reconstitution of CD8+ CD28+ T lymphocytes in a rare case of severe lymphopenia associated with Juvenile Haemochromatosis and Turner's syndrome. [PDF]
Clin Endocrinol (Oxf). 2004 Oct;61(4):437-40. Growth hormone (GH)-induced reconstitution of CD8+ CD28+ T lymphocytes in a rare case of severe lymphopenia associated with Juvenile Haemochromatosis and Turner's syndrome.
BACELAR, C. +8 more
core +1 more source

