Results 91 to 100 of about 1,892,351 (211)

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul   +9 more
wiley   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

open access: yesAmerican Journal of Hematology, Volume 101, Issue 12, Page 2976-2989, December 2026.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho   +27 more
wiley   +1 more source

Remodelling of Skeletal Muscle During Iron Deficiency Anaemia and Recovery After Intravenous Iron Therapy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background The global prevalence of iron deficiency anaemia (IDA) is about 25% and even higher in women of reproductive age and children. IDA can impair skeletal muscle by disrupting oxygen utilization, energy production and contractile function. Haematological effects of intravenous (IV) iron therapy in IDA are well studied, but its impact on
Elke Pertler   +18 more
wiley   +1 more source

Model‐Derived Iopamidol Clearance and Creatinine‐Based Kidney Function Estimates After Trauma: A Retrospective Cohort Study

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 12, December 2026.
Using remnant serum after routine contrast‐enhanced trauma CT, opportunistic iopamidol measurement enabled cohort‐specific, model‐derived clearance estimates that were not reliably captured by creatinine‐based equations. With prospective validation, this approach could provide a timely kidney‐function anchor for dosing renally eliminated medications ...
Manjunath P. Pai   +6 more
wiley   +1 more source

Impact of Heat Block Drying on Morphologic Preservation and Staining of Peripheral Blood Smears

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1341-1347, December 2026.
ABSTRACT Introduction Morphologic evaluation of the peripheral blood smear is critical for diagnosis and ruling out certain hematologic disorders. While air‐drying is standard, some laboratories may use heat blocks to expedite drying. Excessive heat may induce morphologic artifacts, but there is a lack of systematic literature on this practice ...
Ryan C. Shean   +4 more
wiley   +1 more source

Erythrocytapheresis versus phlebotomy in the initial treatment of HFE hemochromatosis patients: results from a randomized trial.

open access: yes, 2011
Contains fulltext : 107773.pdf (Publisher’s version ) (Open Access)BACKGROUND: Standard treatment of newly diagnosed HFE hemochromatosis patients is phlebotomy.
Ferdinand Rombout   +27 more
core   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin   +11 more
wiley   +1 more source

Gamma‐glutamyltransferase and immunoglobulin G in intestinal maturation: Pilot study in preterm and term infants and the influence of breast milk

open access: yesJPGN Reports, Volume 7, Issue 4, Page 592-597, November 2026.
Abstract Gamma‐glutamyltransferase (γGT), a key enzyme in glutathione metabolism, is abundant in colostrum and may indicate neonatal gastrointestinal maturation, although normative serum values and associations with breast milk intake remain unclear, particularly in preterm infants.
Johanna Jakobs   +4 more
wiley   +1 more source

Therapeutic phlebotomy in antenatal and postnatal period of pregnancy

open access: yesInternational Journal of Reproduction, Contraception, Obstetrics and Gynecology
Polycythemia during pregnancy is an uncommon but a high-risk condition that requires careful monitoring and individualized management to prevent maternal and fetal complications. This case report describes a pregnant woman diagnosed with polycythemia in the first trimester, managed successfully with therapeutic venesection under close monitoring.
openaire   +1 more source

Primary Erythrocytosis (Polycythaemia) in a Neutered Male Dog Presenting With Right Hindlimb Lameness

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A young dog presented with progressive unilateral hindlimb lameness and marked erythrocytosis. Diagnostic investigations excluded secondary causes and confirmed primary erythrocytosis. Targeted vascular ultrasonography identified a right external iliac venous thrombus as the suspected cause of lameness.
Robyn Belch   +8 more
wiley   +1 more source

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