Results 91 to 100 of about 14,704 (250)

A phase 1b randomised clinical trial evaluating BBI-001, a non-absorbed oral therapeutic for the treatment of iron overload

Scientific Reports
Non-transfusion-dependent iron overload is the result of excessive dietary iron absorption, most commonly caused in populations of European descent by the genetic disorder HFE-related hemochromatosis (HH).
Curtis Scribner, Jamie Cope, Philip Ryan, John K. Olynyk, John Ryan, J. Daniel Griffin, Cory Berkland   +6 more
doaj   +1 more source

Factors Influencing Evidence‐Informed Symptom Management in Outpatient Malignant Hematology: A Qualitative Description of Patients' and Nurses' Experiences

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To describe patients' and oncology nurses' experiences with symptom management care, and influential barriers and facilitators to enhancing evidence‐informed symptom management in an outpatient malignant hematology unit. Design A qualitative descriptive study embedded within an experience‐based co‐design approach.
Kylie Teggart, Denise Bryant‐Lukosius, Sarah E. Neil‐Sztramko, Tammy De Gelder, Kari Kolm, Cheryl Page, Rebecca Ganann   +6 more
wiley   +1 more source

Effects of Oral Single‐Dose Empagliflozin on Urinary Glucose, Serum β‐Hydroxybutyrate, and Plasma Empagliflozin Concentrations in Healthy Adult Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Empagliflozin is a sodium‐glucose cotransporter‐2 inhibitor used for treating humans with heart failure, among other conditions. This drug could have applications in veterinary cardiology, but whether empagliflozin has biological effects in dogs when administered at dosages approximating human therapeutic dosages is unknown.
Andrea D. Plá Gutierrez, M. Lynne O'Sullivan, Etienne Côté, Sandra McConkey, Butch KuKanich, Stephanie E. Martinez   +5 more
wiley   +1 more source

Ruxolitinib in the treatment of polycythemia vera: patient selection and special considerations. [PDF]

, 2016
The discovery of JAK2 V617F mutation in the mid-2000s started to fill the gap between clinical presentation of polycythemia vera (PV), first described by Vaquez at the end of the 19th century, and spontaneous erythroid colony formation, reported by ...
Alberio, L., Blum, S., Martins, F.
core   +2 more sources

Multiple consecutive daily therapeutic plasma exchange using exclusively albumin replacement fluid in low bleeding risk patients is associated with only rare and mild bleeds

Transfusion, EarlyView.
Abstract Background Therapeutic plasma exchange (TPE) using exclusively albumin replacement fluid depletes coagulation factors, particularly fibrinogen, and concerns about performing multiple consecutive daily procedures due to iatrogenic bleeding exist. Fibrinogen testing to guide bleeding risk stratification is vague.
Jay S. Raval, Joseph R. Griggs, Andres E. Mindiola Romero, Chelsea Reyes, Sarah Mertens, Cynthia Ornelas, Lizabeth Marinaro, Marian A. Rollins‐Raval   +7 more
wiley   +1 more source

Utility of hepatic or total body iron burden in the assessment of advanced hepatic fibrosis in HFE hemochromatosis

Scientific Reports, 2019
Development of advanced hepatic fibrosis in HFE Hemochromatosis (HH) is influenced by hepatic iron concentration (HIC) and age. In patients with HH, it is important to assess the likelihood of cirrhosis and thus the need for confirmatory liver biopsy ...
Justin Chin, Lawrie W. Powell, Louise E. Ramm, Oyekoya T. Ayonrinde, Grant A. Ramm, John K. Olynyk   +5 more
doaj   +1 more source

Staff Time and Motion Assessment for Administration of Erythropoiesis-Stimulating Agents: A Two-Phase Pilot Study in Clinical Oncology Practices [PDF]

, 2013
BACKGROUND: Erythropoiesis-stimulating agents (ESAs) are used for the management of anaemia in patients with non-myeloid malignancies where anaemia is due to the effect of concomitant myelosuppressive chemotherapy.
Arletta van Breda, Jason Legg, John F. Reitan, Patricia K. Corey-Lisle, Sanatan Shreay, Ze Cong   +5 more
core   +1 more source

Transfusion‐related alpha‐gal syndrome: Two new cases expanding the demographic and geographic spectrum, and evidence of a diagnostic gap in allergic transfusion reaction evaluation

Transfusion, EarlyView.
Abstract Background Transfusion‐related alpha‐gal syndrome (TRAGS) has recently been proposed as a cause of allergic transfusion reactions (ATRs) in which alpha‐gal‐specific IgE in sensitized group O (or potentially group A) recipients reacts with epitopes on group B or AB plasma‐containing components.
Mackenzie Foster, Miriam Brown, Angela Mueller, Toufik Tahiri, Kaycie Atchison, Deva Sharma, Cosby A. Stone Jr., Jonathan Tucci, Garrett S. Booth, Jeremy W. Jacobs   +9 more
wiley   +1 more source

A Case Report of Prolonged Hemorrhage Following Traditional Phlebotomy (Fasd)

Journal of Pharmacopuncture
Phlebotomy, a therapeutic method of bloodletting typically performed using a needle, has a traditional technique known as “Fasd.” In this method, blood is extracted by creating a longitudinal incision on a vein (3-5 mm) with a surgical scalpel blade ...
Sajjad Sadeghi
doaj   +1 more source

HASH(0x563d43f53db0) [PDF]

, 2016
HASH(0x563d442146b8)HASH ...
Rosian, K., Winkler, R.
core