Results 101 to 110 of about 14,507 (219)

Longitudinal clinical and preclinical studies identify hetrombopag as a potent chelator for systemic iron overload

HemaSphere, Volume 10, Issue 3, March 2026.
Abstract Iron overload (IO) is a pathological condition characterized by excessive iron accumulation, leading to systemic functional impairment. It frequently occurs in patients with congenital or acquired anemia, such as aplastic anemia, who require long‐term transfusions.
Yufei Zhao, Lingxiao Xing, Baohang Zhang, Wenrui Yang, Xiangrong Hu, Xu Liu, Xiawan Yang, Weiru Liang, Yimeng Shi, Jing Hu, Xiaoxia Li, Rui Kang, Guangxin Peng, Yuan Li, Xiao Hu, Youzhen Xiong, Liping Jing, Weiping Yuan, Sidan Li, Fengkui Zhang, Xin Zhao   +20 more
wiley   +1 more source

Iron metabolism and incidence of metabolic syndrome. [PDF]

, 2015
BACKGROUND AND AIMS: Whether iron metabolism affects metabolic syndrome (METS) is debated. We assessed the association between several markers of iron metabolism and incidence of METS.
Kilani, N., Marques-Vidal, P., Vollenweider, P., Waeber, G.   +3 more
core   +1 more source

Unraveling the role of TP53 mutations in myeloproliferative neoplasms: Molecular mechanisms of leukemic transformation

HemaSphere, Volume 10, Issue 3, March 2026.
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito, Paula Sabbo Bernardo, Jean‐Edouard Martin, Caroline Marty, Isabelle Plo, Iléana Antony‐Debré, Bárbara da Costa Reis Monte‐Mór   +6 more
wiley   +1 more source

Ferritin heavy chain Is the host factor responsible for HCV-Induced inhibition of apoB-100 production and is required for efficient viral infection [PDF]

, 2012
Hepatic fat export occurs by apolipoprotein B-100-containing lipoprotein production, whereas impaired production leads to liver steatosis. Hepatitis C virus (HCV) infection is associated to dysregulation of apoB-100 secretion and steatosis; however, the ...
AMICONE, Laura, Claudia Montaldo, Cristina Di Giacomo, Giuseppe Ippolito, Laura Santangelo, Leopoldo Paolo Pucillo, MANCONE, Carmine, Tonino Alonzi, TRIPODI, Marco, Viviana Costa   +9 more
core   +3 more sources

Cannabis and Alcohol Use and Their Effects on Hematological and Biochemical Parameters: Evidence From the Accra Psychiatric Hospital, Ghana

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Substance use, particularly cannabis and alcohol consumption, presents a growing public health challenge in Ghana, with significant implications for both mental and physical health. While the adverse psychological effects of these substances have been extensively studied, their biochemical impact remains inadequately explored ...
Felix Abekah Botchway, Prince Agyemang, Fati Sidi Yahaya, Emmanuel Baah‐Sackey, Christiana Anim, Emmanuel Abindau, Cecilia Elorm Lekpor   +6 more
wiley   +1 more source

Secondary Polycythemia in A Young Male Patient with Nephrotic Syndrome

Jurnal Penyakit Dalam Indonesia
Polycythemia is a condition characterized by an abnormal increase in the total red blood cell mass and is classified into primary and secondary polycythemia.
Ariani Intan Wardhani, Pringgodigdo Nugroho, Ikhwan Rinaldi, Meilania Sarasawati, Monik Ediana Miranda, Agnes Stephanie Harahap   +5 more
doaj   +1 more source

Tapping but Not Massage Enhances Vasodilation and Improves Venous Palpation of Cutaneous Veins [PDF]

, 2015
This paper investigated whether tapping on the median cubital vein or massaging the forearm was more effective in obtaining better venous palpation for venipuncture. Forty healthy volunteers in their twenties were subjected to tapping (10 times in 5 sec)
Ichimura, Mika, Mori, Masaharu, Ogino, Tetsuya, Sasaki, Shinsuke   +3 more
core   +1 more source

Assessment of Clinical Hematology Laboratory Performance Using Sigma Metrics and Associated Factors in Total Testing Process at the Dessie Comprehensive Specialized Hospital, Northeast, Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Clinical laboratory test results play a fundamental role in clinical decision making, influencing approximately 70% of medical decisions. Numerous studies have shown that errors can occur throughout the total testing process.
Zewudu Mulatie, Endris Ebrahim, Mihreteab Alebachew, Alemu Gedefie, Bruktawit Eshetu, Mihret Tilahun, Habtu Debash, Yeshimebet Kassa, Ermiyas Alemayehu, Tesfaye Gessese, Dereje Mengesha Berta   +10 more
wiley   +1 more source

Erythropoiesis: insights into pathophysiology and treatments in 2017

Molecular Medicine, 2018
Erythropoiesis is a tightly-regulated and complex process originating in the bone marrow from a multipotent stem cell and terminating in a mature, enucleated erythrocyte.
Andrea Zivot, Jeffrey M. Lipton, Anupama Narla, Lionel Blanc   +3 more
doaj   +1 more source

Prevalence and Risk Factors of Anemia in Pregnant Women Attending Antenatal Clinic at a Medical Center in Accra, Ghana: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Anemia during pregnancy remains a major cause of maternal and infant morbidity in Ghana and has broader socioeconomic implications. Its persistence despite existing interventions indicates that factors such as education, occupation, and nutrition require closer evaluation.
Gifty Amewudah, Frank Twum Aboagye, Frank Quarshie, Martin Owusu Asante, Benjamin Ansah‐Agyei, Joseph Otchere, Philip Narteh Gorleku, Maurice Ofoe Gorleku, Margaret Atuahene, Abena Mantebea Ateko, Daniel Eshun   +10 more
wiley   +1 more source