Results 51 to 60 of about 4,893,948 (292)

Therapeutic plasma exchange in glucocorticosteroid-unresponsive patients with Clinically Isolated Syndrome

, 2022
S.489-496Clinically Isolated Syndromes (CIS) summarize clinical features of possible multiple sclerosis (MS) as a first clinical event of the disease. Escalation therapy in CIS episodes comprises high dose glucocorticosteroid (GCS) treatment followed by ...
Mitzner, Steffen, Sauer, Martin, Zettl, Uwe K., Koball, Sebastian, Hickstein, Heiko, Ehler, Johannes, Benecke, Reiner   +6 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Successful therapeutic plasma exchange in cold autoimmune hemolytic anemia in patient with disseminated tuberculosis

Reumatismo, 2021
An association of autoimmune hemolytic anemia with disseminated tuberculosis is an exceedingly rare entity. We describe herein a case of cold hemolytic autoimmune anemia associated with miliary tuberculosis resolved with blood transfusions, therapeutic ...
N. Belfeki, A. Strazzulla, P. Isnard, S. Hamrouni, B. Maamar, P. Soulier, M. Monchi, S. Diamantis   +7 more
doaj   +1 more source

Therapeutic plasma exchange in the treatment of COVID-19 induced cytokine storm: the first Moroccan experience

, 2023
Introduction COVID-19 induced cytokine storm is a well-documented phenomena that contributes significantly in the disease’s evolution and prognosis. Therefore, therapies such as therapeutic plasma exchange, constitute a mainstay of therapeutic management
Iliass Benaini, Ilyass Laaribi, Mohamed Zakaria Bouayed, Houssam Bkiyar, Asmae Yeznasni, Younes Oujidi, Sara Berrajaa, Naima Abda, Brahim Housni   +8 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Adverse effects of intermittent flow therapeutic plasmapheresis in neurology patients in a resource constrained setting

Global Journal of Transfusion Medicine, 2019
Introduction: Therapeutic plasma exchange (TPE) aims at removing harmful substances from patient's plasma. It has become a treatment option in a variety of neurological disorders with good outcome.
Sukanya Baruah, Sundar Periyavan
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Safety and Efficacy of Citrate Anticoagulation in Therapeutic Plasma Exchange: A Clinical Study

Clinics and Practice
Introduction: TPE (therapeutic plasma exchange) has proven to be an extremely effective treatment for a range of conditions, especially over the past 20 years.
Ciprian Gîndac, Tamara Mirela Poroșnicu, Nilima Rajpal Kundnani, Nicoleta Sgăvârdea, Claudiu Rafael Bârsac, Vlad Meche, Adelina Băloi, Laura Alexandra Nussbaum, Ovidiu Horea Bedreag, Dorel Săndesc, Marius Păpurică   +10 more
doaj   +1 more source

Safety and Efficacy of Therapeutic Plasma Exchange in Pediatric Non-Neurological Diseases. [PDF]

Int J Nephrol Renovasc Dis
Monika Miklaszewska,1,2 Magdalena Błasiak,2,3 Przemysław Korohoda,4 Ewelina Jarosz-Wójcik,1,2 Katarzyna Zachwieja,1,2 Karina Madej-Świątkowska,2,3 Dorota Drożdż1,2 1Department of Pediatric ...
Miklaszewska M, Błasiak M, Korohoda P, Jarosz-Wójcik E, Zachwieja K, Madej-Świątkowska K, Drożdż D.   +6 more
europepmc   +2 more sources

Membrane-based therapeutic plasma exchange in dogs: Prescription, anticoagulation, and metabolic response. [PDF]

, 2019
BACKGROUND Therapeutic plasma exchange (TPE) is used increasingly in small animals to remove circulating large molecular products such as antibodies, pathogenic proteins, and protein-bound toxins.
Francey, Thierry, Ariane Schweighauser, Thierry Francey, Schweighauser, Ariane, Francey T, Schweighauser A   +5 more
core   +2 more sources