Results 131 to 140 of about 1,909,516 (350)

Between freedom and despair: Existential challenges and contributions to person-centered and experiential therapy [PDF]

, 2003
This article explores a range of contributions that existential thinking may be able to make to the theory and practice of person-centred and experiential therapy.
Cooper, Mick
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Patient–Oncologist Therapeutic Alliance Among Young Adults with Cancer: Relationships with Meaning and Peace of Mind

, 2021
Katie Darabos, Megan E. Renna
openalex   +2 more sources

Everolimus Exposure as a Predictor of Toxicity in Renal Cell Cancer Patients in the Adjuvant Setting: Results of a Pharmacokinetic Analysis for SWOG S0931 (EVEREST), a Phase III Study (NCT01120249). [PDF]

, 2019
BackgroundS0931 is assessing recurrence-free survival in renal cell carcinoma (RCC) patients randomized to receive everolimus (EVE) versus placebo for one year following nephrectomy.
Heath, Elisabeth I, Lara, Primo, Mack, Philip C, Meng, Maxwell V, Palapattu, Ganesh S, Plets, Melissa, Ryan, Christopher W, Stein, Mark N, Synold, Timothy W, Tangen, Catherine M, Thompson, Ian Murchie, Vogelzang, Nicholas J   +11 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Relation thérapeutique, mal diglossique et injustices épistémiques en contexte réunionnais : comment ouvrir davantage l’espace de parole ?

Éducation et Socialisation
This article explores the therapeutic relationship in the Reunionese context by questioning the contribution of the concept of epistemic injustice to characterize situations where linguistic or situational insecurity is more classically reported, or more
Audrey Noël
doaj   +1 more source

Kinetic Analysis of Therapeutic Doses of &beta;-Blockers for Angina Pectoris Based on Receptor Occupancy Theory : Relationship between &beta;<SUB>1</SUB>-Receptor Occupancy or Vasodilative Action and Dose

, 1999
Yasuhiko Yamada, Kyoko Matsuyama, Risa Takayanagi, Hajime Kotaki, Yasufumi Sawada, Tatsuji Iga   +5 more
openalex   +2 more sources

RELATIONSHIP OF THERAPEUTIC COMMUNICATION WITH ANXIETY OF FIRST ACTIVE PHASE LABOR PATIENTS IN DR. SOEKARDJO TASIKMALAYA’S HOSPITAL

, 2021
Lina Marlina, Reni Nurdianti, Dewi Sri Handayani   +2 more
openalex   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source