Results 191 to 200 of about 1,909,516 (350)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Therapeutic relationship nurse-patient in hemodialysis therapy. [PDF]

Nurs Forum, 2021
Hreńczuk M.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

“Heard with the eyes” : Personal equation and fluid self-state communication in the therapeutic relationship

, 2013
C. Bressi
openalex   +1 more source

ePROMs are Best Used Alongside 'A High-Quality Conversation' as Part of a Therapeutic Relationship. A Qualitative Study of Children with Life-Altering Skin Conditions. [PDF]

Patient
Tyack Z, Simons M, Hartshorn E, Kimble RM, Killey J.   +4 more
europepmc   +1 more source

Therapeutic relationship elements and therapy session outcomes: Protocol for a longitudinal study of the patient's perspective. [PDF]

Open Res Eur, 2023
Stefana A, Fusar-Poli P, Vieta E, Youngstrom EA.   +3 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Association Between Patient-Specific Factors and the Therapeutic Relationship in Direct Access Physiotherapy for Higher Education Students-An Observational Cross-Sectional Study. [PDF]

Physiother Res Int
Riska HE, Karppinen JI, Heikkala ME, Nikander RP, Villberg JJ, Hautala AJ.   +5 more
europepmc   +1 more source

Connecting and Healing: The Role of Existential Isolation in Mediating the Impact of the Therapeutic Relationship on Canadian Men's Mental Health Outcomes. [PDF]

Am J Mens Health, 2022
Storey QK, Kealy D, Seidler ZE, Oliffe JL, Rice SM, Ogrodniczuk JS.   +5 more
europepmc   +1 more source