Results 141 to 150 of about 18,082,299 (299)
Arquivos Brasileiros de Cardiologia, 2013 Diversos estudos relataram os benefícios dos betabloqueadores (BB) para pacientes com insuficiência cardíaca sistólica. No entanto, muitos pacientes hospitalizados em decorrência de insuficiência cardíaca aguda já estão usando os BB e requerem ...
Luiz Carlos Santana Passos +3 more
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Coolmine Therapeutic Community. A year of change: annual report 2006.
, 2007 The therapeutic community model is a treatment and rehabilitation approach where clients live in small structured drug-free communities. The goal is to encourage psychological and lifestyle changes to enable people to maintain a drug-free existence.
core
The Therapeutic Use of Natural Products in Myopia Prevention: Recent Applications. [PDF]
Mol Nutr Food ResWang G, Ren C, Dong X, Zhao L, Guo B.
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The Therapeutic Use of Self by Mental Health Nurses: An Evolving Practice. [PDF]
Int J Ment Health NursHungerford C, Blanchard D, McCloughen A.
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Use of Therapeutic Outcome Measures by Australian Psychotherapists and Counsellors
# Background Outcome measures are increasingly emphasised as effective tools in Australian mental health policy. However, limited understanding exists about usage patterns and barriers among counsellors and psychotherapists practising in Australia.
Day, E. +5 more
core +1 more source
Therapeutic Use of Medical Cannabis Beyond Pain Management in Physical Medicine and Rehabilitation. [PDF]
Arch Intern Med ResCameron A, Fraix MP, Agrawal DK.
europepmc +1 more source