Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]
, 2020 Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I +3 more
core +2 more sources
The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
core +1 more source
Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles
Stem Cells Translational Medicine, 2017 Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell‐related approaches, has underlined the need for standardization and coordination of development efforts.
Agnes T. Reiner +25 more
semanticscholar +1 more source
Ustekinumab in Real-Life Practice: Experience in 116 Patients with Moderate-To-Severe Psoriasis
Acta Médica Portuguesa, 2019 Introduction: Ustekinumab is a monoclonal antibody directed against the p40 subunit common to both IL-12 and IL-23 cytokines. Although the evidence of ustekinumab efficacy and safety in clinical trials is extensively recognized, data on its use in ...
Inês Raposo +4 more
doaj +1 more source
Beyond “#endpjparalysis”, tackling sedentary behaviour in health care [PDF]
, 2019 Reducing sedentary behaviour after hospitalization starts with reducing sedentary behaviour whilst in hospital. Although we have eradicated immobilisation as a therapeutic tool due to its potent detrimental effects, it is still in systemic use within ...
Chastin, Sebastien F.M. +5 more
core +4 more sources
Analysis of Characteristics of Peripheral Arterial Ischemia in Premature Babies and Effects of Nitroglycerin Patch Application [PDF]
Child Health Nursing Research, 2020 Purpose The aim of this retrospective study was to analyze the characteristics of peripheral arterial ischemia and tissue necrosis in premature babies, as well as the effects of nitroglycerin.
Jeongeun Kim, Jin Won Lee, Dong Yeon Kim
doaj +1 more source
How to introduce yourself to patients [PDF]
, 2016 Rationale and key points This article explores the process of introducing yourself to patients. This is an essential interaction because it forms the basis of the therapeutic nurse-patient relationship.
Guest, Mags
core +2 more sources
PLoS ONE, 2017 Resveratrol (RSV), a polyphenolic compound and naturally occurring phytoalexin, has been reported to exert cardio-protective effects in several animal studies.
H. Shoukry +8 more
semanticscholar +1 more source
Highly proliferative ameloblastic fibroma: A rare entity
Contemporary Clinical Dentistry, 2018 Ameloblastic fibroma (AF) is a rare odontogenic neoplasm which is commonly seen in the second decade of life. It is seen most frequently in the mandibular posterior region.
Appasab Sanadi +3 more
doaj +1 more source
“Mesenchymal stem cells”: fact or fiction, and implications in their therapeutic use
F1000Research, 2017 The concept of a post-natal “mesenchymal stem cell” (“MSC”) originated from studies focused on bone marrow stromal cells (BMSCs), which are non-hematopoietic adherent cells, a subset of which are skeletal stem cells (SSCs), able to form cartilage, bone ...
P. Robey
semanticscholar +1 more source