Results 61 to 70 of about 2,453,999 (317)

Coolmine Therapeutic Communities. Helping people help themselves: annual report 2008. [PDF]

open access: yes, 2010
Therapeutic Communities (TC) are designed to foster change and positive growth in their clients, emphasising group work and the taking of personal responsibility within a highly structured environment.

core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Exploring the Link between Uric Acid and Osteoarthritis

open access: yesFrontiers in Medicine, 2017
Both gout and osteoarthritis (OA) are common forms of arthritis that inflict a huge burden to an aging population with the increasing prevalence of obesity. Clinicians have long observed the link between these two conditions. In this review, we summarize
Cheryl Ann Ma   +2 more
doaj   +1 more source

Medicinal use of cannabis: background and information paper [PDF]

open access: yes, 2014
Provides an overview of what is known about medicinal cannabis use in Australia, the current state of the scientific and medical evidence for its use, and problems with the current situation in Australia.

core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Orbital abscess: Management and outcome

open access: yesIndian Journal of Ophthalmology, 2000
Purpose: To discuss the diagnosis, management and outcome of various types of orbital abscess. Methods: The medical records of 13 patients diagnosed and treated for orbital abscess were reviewed. The sources of infection included: paranasal sinusitis (n =
N Suneetha   +3 more
doaj  

Role of Old Antibiotics in the Era of Antibiotic Resistance. Highlighted Nitrofurantoin for the Treatment of Lower Urinary Tract Infections

open access: yesAntibiotics, 2014
Bacterial infections caused by antibiotic-resistant isolates have become a major health problem in recent years, since they are very difficult to treat, leading to an increase in morbidity and mortality.
Maria Jose Munoz-Davila
doaj   +1 more source

Australian professional identity in therapeutic recreation : exploring perspectives from the field

open access: yes, 2019
The purpose of this case study was to explore the emerging Australian professional identity in the field of Therapeutic Recreation (TR). Within Australia, the field most closely associated with TR is Diversional Therapy (DT).
Truong, Son (R17154)   +1 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Evaluation of Anti-inflammatory and Antioxidant Properties of Persea Americana and Syzygium Aromaticum-based Herbal Mouthwash Formulation: An In-vitro Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Medicinal plants and their substances are used as adjunctive therapies for a range of acute and chronic inflammatory diseases. Syzygium aromaticum and Persea americana, in particular, have demonstrated beneficial effects, including anti ...
S Dharini   +3 more
doaj   +1 more source

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