Results 11 to 20 of about 11,729 (255)

Confusion of Therapeutic Approaches [PDF]

open access: yesDeutsches Ärzteblatt international, 2014
Schlitt et al. in their review article focused on cardiotoxic oncological treatments (1). Adequate management of adverse effects of cardiotoxic treatments ensures optimal results of oncological treatment. In the article by Schlitt et al., an algorithm was proposed for monitoring, prevention, and treatment in the context of cardiotoxicity, including the
Ivanyi, Philipp   +2 more
openaire   +2 more sources

C9orf72-Related Neurodegenerative Diseases: From Clinical Diagnosis to Therapeutic Strategies

open access: yesFrontiers in Aging Neuroscience, 2022
Hexanucleotide expansion in C9orf72 has been related to several phenotypes to date, complicating the clinical recognition of these neurodegenerative disorders.
Stefania Zampatti   +7 more
doaj   +1 more source

PHARMACOGENETICS APPROACH TO THERAPEUTICS [PDF]

open access: yesClinical and Experimental Pharmacology and Physiology, 2006
1. Pharmacogenetics refers to the study of genetically controlled variations in drug response. Functional variants caused by single nucleotide polymorphisms (SNPs) in genes encoding drug-metabolising enzymes, transporters, ion channels and drug receptors have been known to be associated with interindividual and interethnic variation in drug response ...
Seok Hwee, Koo, Edmund Jon Deoon, Lee
openaire   +2 more sources

Marine-Inspired Drugs and Biomaterials in the Perspective of Pancreatic Cancer Therapies

open access: yesMarine Drugs, 2022
Despite its low prevalence, pancreatic cancer (PC) is one of the deadliest, typically characterised as silent in early stages and with a dramatically poor prognosis when in its advanced stages, commonly associated with a high degree of metastasis.
Andreia S. Fernandes   +4 more
doaj   +1 more source

El Continuun causal del envejecimiento: la detección precoz de la demencia y el papel de los factores protectores y de riesgo

open access: yesActa Neurológica Colombiana, 2023
The prevalence of cognitive disorders and dementia increases with age and represents a high cost to society and health services. Some authors have suggested an ongoing process that leads from the cognitive impairments to dementia, with a presentation ...
Carolina Restrepo   +2 more
doaj   +2 more sources

Nanodelivery Strategies for Skin Diseases with Barrier Impairment: Focusing on Ceramides and Glucocorticoids

open access: yesNanomaterials, 2022
The human epidermis has a characteristic lipidic composition in the stratum corneum, where ceramides play a crucial role in the skin barrier homeostasis and in water-holding capacity.
Cíntia Almeida   +3 more
doaj   +1 more source

Approaches to the third ventricle

open access: yesBrazilian Neurosurgery, 2012
The authors review the main technical approaches to the third ventricle, the most common surgical indications and their results. The traditional open techniques are characterized by low rate of residual lesion and risk, although low, epilepsy ...
Ricardo Brandão Fonseca   +2 more
doaj   +1 more source

Targeted Therapy with Sirolimus and Nivolumab in a Child with Refractory Multifocal Anaplastic Ependymoma

open access: yesReports, 2021
Pediatric ependymoma (EPN) is the third most common central nervous system (CNS) tumor, with 90% arising intracranially. Management typically involves maximal surgical resection and radiotherapy, but patients’ outcome is poor.
Katia Perruccio   +9 more
doaj   +1 more source

Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2022
Tissue engineering is a novel regenerative approach in the medicinal field that promises theregeneration of damaged tissues. Moreover, tissue engineering involves synthetic and naturalbiomaterials that facilitate tissue or organ growth outside the body ...
Varuna Naga Venkata Arjun Uppuluri   +3 more
doaj   +1 more source

Vertigem posicional paroxística benigna sem nistagmo: diagnóstico e tratamento Benign paroxysmal positional vertigo without nystagmus: diagnosis and treatment

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
O aparecimento do nistagmo nos testes para diagnosticar a VPPB ainda é considerado importante na caracterização clínica da VPPB. Contudo, na prática cotidiana, existem casos de vertigem gerada pelos movimentos cefálicos, que não se acompanham deste sinal
Gabriella Assumpção Alvarenga   +2 more
doaj   +1 more source

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