The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches [PDF]
Frontiers in ImmunologyThe coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant proportion of them
Roxana Gheorghita +15 more
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Insights into the Pathogenesis of HS and Therapeutical Approaches [PDF]
Biomedicines, 2021 Hidradenitis suppurativa (HS) is a debilitating, chronic, (auto)inflammatory disease primarily affecting apocrine gland-rich areas of the body. Although pathogenic mechanisms responsible for HS have not yet been fully elucidated, it is a multifactorial ...
Elia Rosi +6 more
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Case Report: Personalized Therapeutical Approaches with Lenalidomide in Del(5q): A Case Series [PDF]
Frontiers in Oncology, 2022 Myelodysplastic Syndrome (MDS) with del(5q) represents a unique WHO entity, which is often treated with lenalidomide according to standard clinical practice. Guidelines concerning treatment duration have thus far not been implemented, but rather comprise
Anna Stein +3 more
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The Double-Edged Sword of Oxidative Stress in Skin Damage and Melanoma: From Physiopathology to Therapeutical Approaches [PDF]
Antioxidants, 2022 The skin is constantly exposed to exogenous and endogenous sources of reactive oxygen species (ROS). An adequate balance between ROS levels and antioxidant defenses is necessary for the optimal cell and tissue functions, especially for the skin, since it
Monica Emanuelli +8 more
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Systems Biology approaches to cancer: towards new therapeutical strategies and personalized approaches [PDF]
Molecular & Cellular Oncology, 2019 Network approaches are ubiquitous, from social and ecological systems up to complex biological processes. In our recently published work we used the network framework for a Systems Medicine approach to multiple cancer types, in order to highlight ...
Daniel Remondini
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Solitary fibrous tumour: histological discoveries, behavioural aspects, risk assessment and therapeutical approaches [PDF]
Therapeutic Advances in Medical OncologySolitary fibrous tumours (SFT) are fibroblastic mesenchymal tumours that can develop virtually at any site. It usually affects adults, and its incidence is estimated as 1 new case per million people per year.
Claudia Di Prata +14 more
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Hemophilia: a biography on therapeutical approaches [PDF]
Clinical and Biomedical Research, 2023 The history of hemophilia is ancient, with descriptions dated to the 2nd century AD. The first modern narratives appeared in 1800s, when total blood transfusion was the only available treatment and life expectancy was remarkably low.
Dayenne Catelli +7 more
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Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal [PDF]
The Journal of Headache and Pain, 2017 Background Hemicrania continua (HC), paroxysmal hemicrania (PH) and short lasting neuralgiform headache attacks (SUNCT and SUNA) are rare syndromes with a difficult therapeutic approach.
Carlo Baraldi +4 more
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Obesity and lymphedema in geriatrics: combined therapeutical approaches [PDF]
BMC Geriatrics, 2010 Campisi C +4 more
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European Journal of Histochemistry, 2022 Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Despite progress in the last decades, there are still no reliable biomarkers for the diagnosis of and prognosis for GC.
Michael W.L. Quirino +7 more
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